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EC number: 203-782-3
CAS number: 110-60-1
Based on the readily biodegradable classification tested according to
OECD 301 B test (Desmares- Koopmans, 2009) 1,4 diaminobutane is not
(very) persistent , not P and vP.
The octanol/water partition coefficient (log Kow = -0,65, Source: Safety
Data Sheet WorldWise v.3.02, 1 September 2006) meets the criterion of
log Kow < 4,5, from which it can be concluded that 1,4 diaminobutane is
not a bioaccumulating substance, not B and vB.
The only available aquatic toxicity data from a study is the 96h-LC50
value in fish of 730 mg/l (Vaessen P, Meijers J, 1984). Although this
information is considered reliable with restrictions (reliability 2),
this value is used in this toxicity assessment. The toxicity criterion
of EC50/LC50 < 0,1 mg/l is not fulfilled (about a factor 7000 higher)
therefore the substance 1,4 diaminobutane is considered not to be toxic
according to the short-term aquatic toxicity.
The data on persistence, bioaccumulation and toxicity do not fulfil the
screening criteria of Annex XIII of the REACH regulation (table C.1-1
and C.1-2) and should therefore be considered not to be a PBT or vPvB
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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