Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 937-417-0 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 21.1.2008-1.2.2008
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 008
- Report date:
- 2008
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.2 (Acute Toxicity for Daphnia)
- Deviations:
- yes
- Remarks:
- The study was perfomed without the analytical determination of the test substance concentrations. For all evaluations and results nominal concentrations of the test substance were used.
- GLP compliance:
- yes
Test material
- Reference substance name:
- Ashes (residues)
- EC Number:
- 268-627-4
- EC Name:
- Ashes (residues)
- Cas Number:
- 68131-74-8
- Test material form:
- solid: bulk
- Details on test material:
- - Name of test material (as cited in study report): Ashes (residues)
- Substance type: technical product
- Physical state: solid
- Main components: SiO2 (42.12%), Al2O3 (32.16%), Fe2O3 (10.88%), TiO2, MnO, MgO, CaO, Na2O, K2O, SO3 - constituents with content less than 10%
- Expiration date of the lot/batch: unlimited
- Appearance: greyish black powder
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- no
- Details on test solutions:
- PREPARATION OF SOLUTIONS OF TEST SUBSTANCE:
Since the test substance is poorly soluble in dilution water at concentrations needed for the test, the saturated solution of the test substance in dilution water was used as stock solution. 50 mg of the test substance was weighed into 500 mL of the dilution water for preliminary test and limit test. These mixtures were stirred on a shaft stirrer throughout two days, ultrasonicated for 10 minutes and filtered through 0.45 micron filter. The concentrations of solutions used in the preliminary and limit test were obtained by dilution of the stock saturated solution with dilution water.
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Common name: Daphnia magna
- Strain: Straus
- Source: own laboratory breeding
- Age at study initiation: young daphnia born in 24 hours
- Method of breeding: aperiodic parthenogenesis
- Feeding during test: no
- Lighting: natural variation of daily light and dark
- Number of test animals: 20 for each concentration and control in preliminary test, 20 for each concentration and control in limit test
- Aeration: without aeration
ACCLIMATION
- Acclimation period: The grow-up gravid females are separated into dilution water. Young daphnia born in 24 hours are segregated to the handling container from which they entered the experiment.
- Acclimation conditions (same as test or not): same as test
- Type and amount of food: a mixture of algae
- Health during acclimation (any mortality observed): healthy daphnia
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 48 h
Test conditions
- Hardness:
- Preliminary test: content of (Ca+Mg) in dilution water: 2.61 mmol.L-1
Limit test: content of (Ca+Mg) in dilution water: 2.59 mmol.L-1 - Test temperature:
- 20+/- 2 °C, with a variation of +/- 1°C at each individual test
- pH:
- Preliminary test: pH of dilution water 7.9
Limit test: pH of dilution water 8.0 (see table 6) - Dissolved oxygen:
- Study conditions-concentration of dissolved oxygen: higher than 3 mg/L
At the beginning and the end of the test the oxygen content was measured-see table 5. - Nominal and measured concentrations:
- Nominal concentration: See table 1 and table 4.
- Details on test conditions:
- TEST SYSTEM
- Test vessel: open beaker
- Material, fill volume: glass, 50 ml of test solution
- Aeration: no
- No. of organisms per vessel: 10
- No. of vessels per concentration (replicates): 2
- No. of vessels per control (replicates): 2
- Biomass loading rate: one young daphnia per 5 ml of test solution
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: Standard dilution water was prepared just before the test.
The dilution water should be of pH 7.8 +/- 0.2. The sum of Ca + Mg ions should be approx. 2.5 mmol.L-1.
- Conductivity of distillated water: 0.135 mS.m-1
- Intervals of water quality measurement: just before the test
OTHER TEST CONDITIONS
- Photoperiod: natural daily light and dark
EFFECT PARAMETERS MEASURED:
The daphnia immobilisation was observed after 24 and 48 hours. At the beginning and the end of the test the ambient temperature, the oxygen content and pH value were measured.
TEST CONCENTRATIONS
The stock saturated solution of the test substance in dilution water was prepared for limit test. The limit test was performed in range nominal concentrations from 62 mg.L-1 to 100 mg.L-1. For the test was used geometric concentration series of the test substance with factor 1.1. - Reference substance (positive control):
- yes
- Remarks:
- pottasium dichromate
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 24 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- EC100
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 24 h
- Dose descriptor:
- EC100
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Details on results:
- - Behavioural abnormalities: not observed
- Observations on body length and weight: not observed
- Other biological observations: not observed
- Mortality of control: none
- Other adverse effects control: not observed - Results with reference substance (positive control):
- - Results with reference substance valid? yes
- EC50: The sensitivity of the test species and correctness of test performance is periodically verified in three-month period by testing with the reference substance, potassium dichromate.
The results of the verification test with K2Cr2O7 are the following:
24h – EC50 = 1.15 mg.L-1 (95 % confidence limit: 0.81 – 1.49 mg.L-1)
48h – EC50 = 0.80 mg.L-1 (95 % confidence limit: 0.71 – 0.88 mg.L-1)
Any other information on results incl. tables
Limit test
Table 4.Immobilisation of daphnia – limit test
Nominal concentration |
mg·L-1 |
100 |
91 |
83 |
75 |
68 |
62 |
C |
Saturated solution dosing |
mL·L-1 |
1000 |
910 |
830 |
750 |
680 |
620 |
C |
Number of live animals |
24 hours/1stseries |
10 |
10 |
10 |
10 |
10 |
10 |
10 |
Number of live animals |
24 hours/2ndseries |
10 |
10 |
10 |
10 |
10 |
10 |
10 |
Number of live animals |
24 hours/total |
20 |
20 |
20 |
20 |
20 |
20 |
20 |
Immobilisation % |
24 hours |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
Number of live animals |
48 hours/1stseries |
10 |
10 |
10 |
10 |
10 |
10 |
10 |
Number of live animals |
48 hours/2ndseries |
10 |
10 |
10 |
10 |
10 |
10 |
10 |
Number of live animals |
48 hours/total |
20 |
20 |
20 |
20 |
20 |
20 |
20 |
Immobilisation % |
48 hours |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- No immobilisation was observed in limit test. Therefore, exact values of EC50 could not be calculated and the values of EC are given in the form of a range. The NOEC and EC100 values are identified by direct observation.
The nominal concentrations of the test substance were used for all evaluations and results. - Executive summary:
The test substance, Ashes (residues),was tested in acute immobilisation test on daphnia.
The test was performed according to EU method C.2. - Acute toxicity for Daphnia, Directive 92/69/EEC, Published in O.J.L 383A, 1992.
Since the test substance is poorly soluble in dilution water it was not possible to achieve the concentration of 100 mg·L-1. For this reason a saturated solution of the test substance in dilution water was prepared for preliminary and limit test.
The preliminary test was performed in range of test substance nominal concentrations 1 – 100 mg·L-1. Based on no toxicity of the test substance found in preliminary test, the limit test was performed. The limit test was performed in range of test substance nominal concentrations 62 – 100 mg·L-1. The test was performed as static.
The study was performed without the analytical determination of the test substance concentrations. The nominal concentrations of the test substance were used for all evaluations and results.
Test results:
24–hour EC50>100 mg·L-1(nominal concentration)
48–hour EC50>100 mg·L-1(nominal concentration)
24–hour NOEC = 100 mg·L-1(nominal concentration)
48–hour NOEC = 100 mg·L-1(nominal concentration)
24–hour EC100>100 mg·L-1(nominal concentration)
48–hour EC100>100 mg·L-1(nominal concentration)
Classification of the test substance on the basis of hazard to aquatic environment was performed according to the Directive 93/21/EEC, Annex IV (article 5.2.1.).
According to the classification criteria given in quoted Directivethe test substance,Ashes (residues), is not assigned to any of quoted toxicity categories.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.