Registration Dossier
Registration Dossier
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EC number: 939-717-7 | CAS number: 1474044-79-5
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
Based on the structural similarity of CALCIUM BIS( DI C8-C10, BRANCHED, C9 RICH, ALKYLNAPHTHALENE SULPHONATE) and BARIUM BIS( DI C8-C10, BRANCHED, C9 RICH, ALKYLNAPHTHALENE SULPHONATE)
read-across is valid between the substances.Therefore CALCIUM BIS( DI C8-C10, BRANCHED, C9 RICH, ALKYLNAPHTHALENE SULPHONATE)
is not genotoxic based on the results of the Ames bacterial reverse mutation assay, the mouse L5178Y lymphoma test (MLA) and human peripheral lymphocytes test conducted with the barium analog..Short description of key information:
The genetic toxicity of CALCIUM BIS( DI C8-C10, BRANCHED, C9 RICH, ALKYLNAPHTHALENE SULPHONATE) is based on testing with the close analog BARIUM BIS( DI C8-C10, BRANCHED, C9 RICH, ALKYLNAPHTHALENE SULPHONATE). The Barium analog was found to be non-mutagenic in the Ames bacterial reverse mutation assay and the mouse lymphoma test (MLA). The substance was did not cause chromosomal aberrations in human peripheral lymphocytes.
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
The substance, Ca-DNNSA, is expected to be negative in three in vitro genetic toxicity tests (Ames test, mouse lymphoma cell mutation assay and chromosome aberration test in human lymphocytes) and thus is not classified for genetic toxicity according to CLP (Regulation EC No 1272/2008) or DSD (Directive 67/548/EEC).
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