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Diss Factsheets

Physical & Chemical properties

Solubility in organic solvents / fat solubility

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Administrative data

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Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with national standard methods
Justification for type of information:
Data is from experimental study report
Qualifier:
according to guideline
Guideline:
other: Gravimetric method
Principles of method if other than guideline:
Weight of the test chemical (fat) to dissolve in Organic Solvent to form a homogeneous solution of the solute in the solvent

GLP compliance:
no
Other quality assurance:
ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)
Key result
Medium:
methanol
Solubility:
28 000 mg/L
Temp.:
23 °C
Remarks on result:
other: soluble
Conclusions:
The solubility of test chemical in methanol was determined to be 2800 mg/L at 24°C, indicating that this substance is soluble in methanol.
Executive summary:

The solubility of test chemical in methanol was determined to be 2800 mg/L at 24°C, indicating that this substance is soluble in methanol.

Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with national standard methods
Justification for type of information:
Experimental test result performed using standard test guideline
Qualifier:
according to guideline
Guideline:
other: Gravimetric method
Principles of method if other than guideline:
Weight of the chemical substance (fat) to dissolve in Organic Solvent to form a homogeneous solution of the solute in the solvent
GLP compliance:
no
Key result
Medium:
other: petroleum ether
Solubility:
8 000 mg/L
Temp.:
23 °C
Remarks on result:
other: soluble
Conclusions:
The solubility of test chemical in petroleum ether was determined to be 8000 mg/L at 23°C, indicating that this substance is soluble in petroleum ether.
Executive summary:

The solubility of test chemical in petroleum ether was determined to be 8000 mg/L at 23°C, indicating that this substance is soluble in petroleum ether.

Description of key information

Based on the available data from study report, the solubility of test chemical in methanol and petroleum ether at 24°C was determined to be 2800 mg/l and 8000 mg/L, respectively indicating that the test chemical is soluble in both methanol and petroleum ether.

Key value for chemical safety assessment

Solubility in organic solvents at 20°C:
2 800 mg/L

Additional information

Based on the available data from study report, the solubility of test chemical in methanol and petroleum ether at 24°C was determined to be 2800 mg/l and 8000 mg/L, respectively indicating that the test chemical is soluble in both methanol and petroleum ether.