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Physical & Chemical properties

Vapour pressure

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vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Reason / purpose for cross-reference:
reference to same study
Reason / purpose for cross-reference:
reference to other study
according to guideline
OECD Guideline 104 (Vapour Pressure Curve)
GLP compliance:
yes (incl. QA statement)
Dept. of Health, UK
Type of method:
effusion method: vapour pressure balance
Key result
Test no.:
25 °C
Vapour pressure:
0.048 Pa

summary of the results:

 Run  Log10 [Vp(25°C)]
 1  -1.314
 2  -1.307
 3  -1.320
 4  -1.337
 5  -1.327
 6  -1.315
 7  -1.377
 8  -1.377
 9  -1.375
 10  -1.378


Vapour Pressure


0.048 Pa

The vapour pressure of the active ingredient monoethanolamine thioglycolate has been determined to be 4.8 x 10exp-2 Pa at 25 °C.
Executive summary:

An attempt was made to determine the vapour pressure of the test material using the isoteniscope method. This attempt was unsuccessful, it appears that the water removed under the vaccuum conditions, then the remaining monoethanolamine thioglycolate decomposed without boiling. Therefore, the vapour pressure balance method were used to determine the Vp of monoethanolamine thioglycolate (active ingredient).

Description of key information

Ten measurements were performed according to OECD TG 104 (EU A4).

Key value for chemical safety assessment

Vapour pressure:
0.048 Pa
at the temperature of:
25 °C

Additional information

The sequence of ten runs was started after a sample of the test material had been held under vaccum for 215.75 h. Temperature and pressure readings were taken between 25 and 35°C with one hour dwell at 25 °C between the runs.