Registration Dossier
Registration Dossier
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EC number: 931-597-4 | CAS number: -
Toxicity to birds
Administrative data
Link to relevant study record(s)
- Endpoint:
- long-term toxicity to birds
- Data waiving:
- other justification
- Justification for data waiving:
- other:
Reference
Description of key information
According to column 2 of REACH Annex X (9.6.1), the study does not need to be conducted since results from mammalian toxicity testing indicate that Ash has a low potential to cause adverse long term or reproductive effects.
Key value for chemical safety assessment
Additional information
No long-term or reproductive toxicity tests on birds are available. However, a repeated dose toxicity experiment with rats exposed to Ash via ingestion in a 28-day GLP-complient, guideline test did not indicate any serious toxic effects. This result is supported by
several inhalation toxicity studies of coal fly ash in mammals as well as an observational study on workers exposed to pulverized fuel ash. The toxicological profile of Ash in birds can therefore be predicted from the mammalian studies. According to them, no toxic effects are likely to occur in birds at relevant exposure levels.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
