Registration Dossier
Registration Dossier
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EC number: 700-103-7 | CAS number: -
Bioaccumulation: aquatic / sediment
Administrative data
- Endpoint:
- bioaccumulation in aquatic species: fish
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 2007-2008
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 008
- Report date:
- 2008
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 305 B (Bioaccumulation: Semi-static Fish Test)
- GLP compliance:
- no
Test material
- Reference substance name:
- R&D Reference code synonymous with CASSYRANE
- IUPAC Name:
- R&D Reference code synonymous with CASSYRANE
- Test material form:
- other: colourless liquid
- Details on test material:
- GR-86-3794 (synonymous with CASSYRANE)
Lot No. LDP0700006
Purity: 97.8%
Date of Expiry : 29 July 2009
Constituent 1
- Radiolabelling:
- no
Test organisms
- Test organisms (species):
- Carassius auratus
Study design
- Route of exposure:
- aqueous
- Test type:
- semi-static
- Water / sediment media type:
- natural water: freshwater
- Total exposure / uptake duration:
- 30 d
Test conditions
- Hardness:
- Approx. 100 mg CaCO3/L
- pH:
- pH 6.4 to 6.7
Results and discussion
Bioaccumulation factoropen allclose all
- Type:
- BCF
- Value:
- >= 34.3 - <= 63.1 L/kg
- Basis:
- whole body w.w.
- Remarks on result:
- other: Conc.in environment / dose:1 mg/L
- Type:
- BCF
- Value:
- >= 31.8 - <= 48.1 L/kg
- Basis:
- whole body w.w.
- Remarks on result:
- other: Conc.in environment / dose:10 mg/L
Applicant's summary and conclusion
- Conclusions:
- The bioconcentration of CASSYRANE in Carassius auratus exposed over a period of 30 days in an OECD 305B test set-up under 48-hour semi-static renewal conditions was determined to be on average 39 L/kg wet wt. at the 10 mg/L exposure level and 52 L/kg wet wt at the 1 mg/L exposure level.
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