Disodium piperazine-1,4-diethanesulphonate

Guidance on Safe Use

First-aid measures

Description of first aid measures

After inhalation:

Remove from source of exposure. If irritation or signs of toxicity occur, seek medical attention.

After skin contact:

Take off any clothing that the product touched. Rinse skin with running water for 15 to 20 minutes.  Seek

medical attention if irritation or signs of toxicity occur.

After eye contact:

Rinse cautiously with water for several minutes.  Remove contact lenses, if present and easy to do.  Continue

rinsing.  If eye irritation persists, get medical advice/attention.  Wash hands after handling.

After swallowing:

Rinse mouth with water. If irritation or signs of toxicity occur, seek medical attention.

Information for Medical Personnel:

Most important symptoms and effects, both acute and delayed:

None expected

Indication of any immediate medical attention and special treatment needed:

No additional relevant information available.

Fire-fighting measures

Extinguishing media

Suitable extinguishing agents:

Dry chemical, carbon dioxide (CO2), water spray or regular foam.

Caution: CO2 will displace air in confined spaces and may cause an oxygen-deficient atmosphere.

For larger fires: There are no unique chemical or reactivity hazards that would impact firefighting decisions

related to this product.  Use firefighting measures that suit the environment.

Special hazards arising from the substance or mixture

There are no unique chemical or reactivity hazards that would impact firefighting decisions due to the chemicals in

this product.

Advice for firefighters

Protective equipment:

For large fires, wear appropriate heat- and flame-resistant personal protective equipment and an approved

positive-pressure, self-contained breathing apparatus.

Accidental release measures

Personal precautions, protective equipment and emergency procedures

Minimize exposure by using appropriate personal protective equipment. Stop leak if

possible.  Keep unprotected persons away.

Environmental precautions:

Prevent liquid and vapor from entering sewage system, storm drains, surface waters, and soil.

Methods and material for containment and cleaning up:

Blot up small volumes of spilled or spattered product with paper towels or similar materials.

Contain larger spills by placing absorbants around the outside edges of the spill. Absorb with any material

suitable for water-based liquids - e.g. paper towels, universal sorbents, sand, diatomite, sawdust, etc.

Clean the affected area. Suitable cleaners are:

Warm water and detergent or similar cleansing agent

This product contains sodium azide, which is toxic and reactive.  

NOTE FOR LARGE-VOLUME SPILL:  This product contains sodium azide, which reacts with acid to liberate

hydrazoic acid, a very toxic gas.  Select a disinfectant with the following properties if disinfection of materials used

to absorb a large volume of spilled product is required:

Do not use any chemical or product with a pH below 6 to disinfect waste that contains sodium azide. Hydrazoic

acid, a toxic gas, will be released when the pH is lower than 6.

Do not use any chemical or product that contains mercury or any other metal to disinfect waste that contains

sodium azide.  This will create metal azide compounds, which can be highly explosive under pressure or shock

(percussion).

Select a disinfectant that does not bubble, effervesce or otherwise generate aerosols.

-  Do not use excess disinfectant.

-  Failure to follow manufacturer’s directions may lead to unexpected reactions with the waste.

-  Do not use a disinfectant if you do not have the proper facility, equipment and other appropriate protective

measures available to work with it safely.

Dispose of spilled and contaminated material in accordance with Federal, State, and Local regulations.

Handling and storage

Handling

Precautions for safe handling:

Avoid direct contact with material.  If handled, wash thoroughly. Practice general safety precautions.

Information about protection against explosions and fires:

No special measures required.

Conditions for safe storage, including any incompatibilities

Storage:

Requirements to be met by storerooms and containers:

Store only in the original container.

Refer to the package insert or product label for additional information on storage conditions for product

quality.

Information about storage in one common storage facility:

Store in original packaging.

Further information about storage conditions:

Protect from heat and direct sunlight.

Specific end use(s):

No additional relevant information available.

Transport information

Shipping

SpecialProvisions

Shipping

Remarks

Marine transport (UN RTDG/IMDG)

Shipping

Remarks

Air transport (UN RTDG/ICAO/IATA)

Shipping

Special provisions / remarks

Remarks:

Not regulated.

SpecialProvisions

Exposure controls / personal protection

Exposure controls

Personal protective equipment:

General protective and hygienic measures:

Always maintain good housekeeping and follow general precautionary measures. Do not eat, drink or store

food and beverages in areas where chemicals or specimens are used. Wash hands before breaks, after

handling reagents and specimens, and at the end of the workshift.

Breathing equipment:

Normal use and storage of product - respiratory protection is not necessary if room is well ventilated.

Small-volume spills (e.g. small enough to clean up with a paper towel or small sorbent pad) - respiratory

protection should not be necessary if room is well ventilated.

Other unusual conditions (e.g. volume spilled too big to clean up with materials in arm's reach) - Use

appropriate air-purifying respirator if airborne chemical concentrations may exceed the exposure limit (if

any) listed above.

Hazardous Materials Emergencies or Firefighting - use approved respiratory protection.

Take precautions if chemical concentrations exceed the exposure limits (if any) listed above.

Protection of hands:

Wear impervious gloves if hand contact with the material is anticipated.  Dispose of contaminated gloves

after use in accordance with applicable laws and good laboratory practices.

·

Material of gloves and breakthrough time of the glove material:

The glove material must be suitable for use in a microbiological laboratory and have a measured

breakthrough time of at least 30 minutes, such as those with a Class 2 protection index per EN374 (or

equivalent standard applicable in your region). NOTE: This recommendation applies only to the product

stated in this Safety Data Sheet.  When dissolving in or mixing with other substances, contact the

supplier of approved gloves.

Eye protection:

Wear safety glasses or other protective eyewear. If splash potential exists, wear full face shield or goggles.

Body protection:

Normal use: protect personal clothing from spatters and small spills.  Wear a laboratory coat (or other

protective clothing required by your institution). Larger spills (e.g. that can saturate cloth): wear appropriate

water-repellant covering over clothing

Stability and reactivity

Reactivity

Chemical stability:

Thermal decomposition / conditions to be avoided:

No decomposition if used and stored according to specifications.

Possibility of hazardous reactions:

This product contains sodium azide. Sodium azide solutions are reported to:

react with acids to release hydrazoic acid, a very toxic gas. Higher quantities of hydrazoic acid are released as

the solution becomes more acidic (i.e., as the pH of the solution gets lower). Low quantities of hydrazoic acid can

be released from sodium azide in water.

React with certain metals (copper, lead, silver, brass) to form explosive metal azide compounds. Violent

explosions have been reported during plumbing work on drain systems containing accumulations of azide on

copper, lead, brass, or solder.

Conditions to avoid:

No further relevant information available.

Incompatible materials:

No further relevant information available.

Hazardous decomposition products:

No dangerous decomposition products known.

Disposal considerations

Waste treatment methods

There are no uniform EU regulations for the disposal of laboratory waste. In general, laboratory waste is under

special supervision of the authorities.

Recommendation for disposal of unused product:

Dispose in accordance with national, state and local regulations and institutional requirements.  Waste

containing this product may be considered hazardous per state or local regulations.  The following may be

particularly important when identifying appropriate disposal:

Contains sodium azide. Detailednformation about azides in drains is available from the U.S. NIOSH Current Intelligence Bulletin No. 13

(August 16, 1976).

European waste catalogue:

Consult the responsible regulatory body for the assignment of disposal codes according to the European

Waste Catalogue.

The following waste disposal key numbers are possible:

18 01 06: chemicals consisting of or containing dangerous substances

Uncleaned packagings

For disposal of contaminated packaging, refer to applicable local regulations and institutional policies.

Recommendation for disposal of packaging:

Non-contaminated packaging may be used for recycling. Refer to applicable local regulations and institutional

policies.

For disposal of contaminated packaging, refer to applicable local regulations and institutional policies.

Recommended cleaning agent:

Water with cleansing agents, if necessary.