Registration Dossier
Registration Dossier
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EC number: 204-613-6 | CAS number: 123-26-2
Vapour pressure
Administrative data
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 20. Feb. 2019 - 04. July 2019
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 019
- Report date:
- 2019
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- effusion method: Knudsen cell
Test material
- Reference substance name:
- N,N'-ethane-1,2-diylbis(12-hydroxyoctadecan-1-amide)
- EC Number:
- 204-613-6
- EC Name:
- N,N'-ethane-1,2-diylbis(12-hydroxyoctadecan-1-amide)
- Cas Number:
- 123-26-2
- Molecular formula:
- C38H76N2O4
- IUPAC Name:
- 12-hydroxy-N-[2-(12-hydroxyoctadecanamido)ethyl]octadecanamide
- Test material form:
- solid
Constituent 1
Results and discussion
Vapour pressureopen allclose all
- Key result
- Temp.:
- 20 °C
- Vapour pressure:
- 0 Pa
- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa
Applicant's summary and conclusion
- Conclusions:
- The study can be considered as valid. The test item Bisamid has a vapour pressure of 1.37 * 10-06Pa at20°C, which was determined by OECD104.
- Executive summary:
The vapour pressure of Bisamid was determined according to OECD 104 resp. EU A.4 using the effusion method (weight loss). Vapour pressure was examined at nine different temperatures. Three temperatures could be evaluated as they showed reproducible weight loss. For these temperatures, 1/T was plotted against log (p).
Table 3-a: Vapour Pressures (Effusion Method)
Experiment T Mean p Stand. Dev. p RSD p
No. K Pa Pa %
5 363.2 8.93E-04 4.78E-05 5.4%
6 378.2 2.05E-03 5.94E-04 29.0%
7 393.2 6.94E-03 1.17E-03 16.9%
In this table, E-0X represents multiplication with 10-x. Stand. Dev. = Standard Deviation; RSD = Relative Standard Deviation
The graph 1/T vs. log (P) shows a straight line with a correlation coefficient of - 0.9912. For the test item Bisamid, the following vapour pressures at 20 °C and at 25 °C were calculated from the regression equation:
Vapour pressure at 20 °C: 1.37 * 10-06Pa
Vapour pressure at 25 °C: 2.40 * 10-06Pa
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