Registration Dossier
Registration Dossier
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EC number: 203-057-1 | CAS number: 102-81-8
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Acutely harmful to algae.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 21.6 mg/L
- EC10 or NOEC for freshwater algae:
- 6.9 mg/L
Additional information
The toxic effect of 2-dibutylaminoethanol (CAS 102 -81 -8) was tested in a GLP-guideline study according to OECD 201 using Pseudokirchneriella subcapitata as test species (NITE, 2004). The concentrations were analytically verified. The 72 -h ErC50 was determined to be 21.6 mg/L, the NOErC was 3.2 mg/L (results obtained from J-Check database and revalidated in 2014 by BASF SE). The 72 -h ErC10 was calculated to be 6.9 mg/L (original data, recaclulated using ToxRat v2.10; BASF SE, 2014). The ErC10 is the preferred effect value according to REACH Guidance Document R.7b (June 2017, v4.0). It is the relevant effect value for the assessment of the sensitivity of algae to DBEA as well as for the derivation of the PNECs.
In conclusion, DBEA is acutely harmful to algae.
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