Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
256-032-2
CAS no.:
42978-66-5
Index number:
Molecular formula:
C15H24O6
SMILES:
InChI:
Type of substance:
UVCB
Origin:
Organic
Registered compositions:
12
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Warning! According to the harmonised classification and labelling (CLP00) approved by the European Union, this substance is toxic to aquatic life with long lasting effects, causes serious eye irritation, causes skin irritation, may cause an allergic skin reaction and may cause respiratory irritation.

Breakdown of all 2986 C&L notifications submitted to ECHA

Eye Irrit. 2 H319 Harmonised Classification
Skin Irrit. 2 H315 Harmonised Classification
Skin Sens. 1 H317 Harmonised Classification
STOT SE 3 H335 Harmonised Classification
Aquatic Chronic 2 H411 Harmonised Classification
STOT SE 3 H370
Not Classified
Skin Corr. 1C H314
Flam. Liq. 3 H226
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://www.echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://www.echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://www.echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.

Properties of concern

  • Ss
Officially recognised in the EU as Skin sensitising ( Harmonised C&L).
  • Ss
There is broad agreement in that a majority of data submitters agree this substance is Skin sensitising (100% of REACH registrations).

Regulatory activities

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 18 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Notification:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is manufactured and/or imported in the European Economic Area in 100 000 - 1 000 000 tonnes per year.

This substance is used by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

This substance is used in the following products: coating products and inks and toners.

This substance is used for the manufacture of: chemicals.

This substance is used in the following activities or processes at workplace: closed batch processing in synthesis or formulation, roller or brushing applications, transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure and mixing in open batch processes.

Other release to the environment of this substance is likely to occur from: indoor use and outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives).

This substance is used in the following products: coating products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, mixing in open batch processes, transfer of substance into small containers and laboratory work.

Release to the environment of this substance can occur from industrial use: formulation of mixtures.

This substance is used in the following products: polymers, coating products and inks and toners.

This substance is used for the manufacture of: chemicals.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, closed processes with no likelihood of exposure, laboratory work, batch processing in synthesis or formulation with opportunity for exposure, closed, continuous processes with occasional controlled exposure, mixing in open batch processes and roller or brushing applications.

Release to the environment of this substance can occur from industrial use: in the production of articles, as processing aid, as an intermediate step in further manufacturing of another substance (use of intermediates) and for thermoplastic manufacture.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed batch processing in synthesis or formulation, transfer of substance into small containers, laboratory work and closed, continuous processes with occasional controlled exposure.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

ECHA has no data from registration dossiers on the precautionary measures for using this substance. Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • Allnex Belgium NV/SA, Anderlechtstraat 33 1620 Drogenbos Belgium
  • Allnex Belgium NV/SA OR1, Anderlechtstraat 33 1620 Drogenbos Belgium
  • Allnex Belgium NV/SA OR2, Anderlechtstraat 33 1620 Drogenbos Belgium
  • ARKEMA FRANCE, 420 rue d'Estienne d'Orves 92700 COLOMBES France
  • ARKEMA PHOTOCURES, 420 rue d'Estienne d'Orves 92700 Colombes France
  • ARKEMA PHOTOCURES2, 420 rue d'Estienne d'Orves 92700 Colombes France
  • BASF Health and Care Products France S.A.S., 49, Avenue Georges Pompidou 92593 Levallois-Perret Cedex France
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED (Jiangsu Sanmu Group Co., ltd.), Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CRCP GmbH, Am Römerhof 51 60486 Frankfurt am Main Germany
  • DSM Resins BV, Ceintuurbaan 5 8022 AW Zwolle Netherlands
  • Du Pont (U.K.) Limited, London Road 4th Floor, Kings Court SG1 2NG Stevenage Hertfordshire United Kingdom
  • Du Pont de Nemours (Deutschland) GmbH, Hugenottenallee 173-175 D-63263 Neu-Isenburg Hesse Germany
  • IGM Resins B.V., Gompenstraat 49 5145 RA Waalwijk Netherlands
  • KIST Europe Forschungsgesellschaft mbH, Campus E 71 66123 Saarbruecken Germany
  • Luxcontrol S.A. (OR52), 1, Avenue des Terres Rouges 4331 Esch-sur-Alzette Luxembourg
  • REACH24H CONSULTING GROUP, Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland

Substance names and other identifiers

(1-methyl-1,2-ethanediyl)bis[oxy(methyl-2,1-ethanediyl)] diacrylate
EC Inventory, C&L Inventory, REACH pre-registration
(1-methyl-1,2-ethaandiyl)bis[oxy(methyl-2,1-ethaandiyl)diacrylaat (nl)
C&L Inventory
(1-methyl-1,2-ethandiyl)bis[oxy(methyl-2,1-ethandiyl)]diacrylat (da)
C&L Inventory
(1-Methyl-1,2-ethandiyl)bis[oxy(methyl-2,1-ethandiyl)diacrylat (de)
C&L Inventory
(1-metil-1,2-etandiil)bi[oksi(metil-2,1-etandiil)]diakrilatas (lt)
C&L Inventory
(1-metil-1,2-etandiil)bis[oksi(metil-2,1-etandii)] diakrilat (sl)
C&L Inventory
(1-metil-1,2-etandiil)bis[oksi(metil-2,1-etandiil)] diakrilat (hr)
C&L Inventory
(1-metil-1,2-etanediil)bis[oxi(metil-2,1-etanediil)] diacrilat (ro)
C&L Inventory
(1-metil-1,2-etándiil)bisz[oxi(metil-2,1-etándiil)]diakrilát (hu)
C&L Inventory
(1-metil-1,2-etāndiil)bis-[oksi(metil-2,1-etāndiil)]diakrilāts (lv)
C&L Inventory
(1-metyl-1,2-etandiyl)bis[oksy(metyl-2,1-etandiyl)]diakrylat (no)
C&L Inventory
(1-metyl-1,2-etandiyl)bis[oxi(metyl-2,1-etandiyl)]diakrylat (sv)
C&L Inventory
(1-metyyli-1,2-etaanidiyyli)bis[oksi(metyyli-2,1-etaanidiyyli)]diakrylaatti (fi)
C&L Inventory
(1-metüül-1,2-etaandiüül)bis[oksü(metüül-2,1-etaandiüül)diakrülaat (et)
C&L Inventory
(1-метил-1,2-етандиил)бис[окси(метил-2,1-етандиил)] диакрилат (bg)
C&L Inventory
1,2’-dimetyl[(propán-1,2-diyl)bis(oxy)]dietyl-diakrylát (sk)
C&L Inventory
diacrilato de (1-metil-1,2-etanodiil)bis[oxi(metil-2,1-etanodiilo)] (es)
C&L Inventory
diacrilato di (1-metil-1,2-etandiil)bis[ossi(metil-2,1-etandiile)] (it)
C&L Inventory
diacrylate de (1-méthyl-1,2-éthanediyl)bis[oxy(méthyl-2,1-éthanediyle)] (fr)
C&L Inventory
diakrylan (1-metyloetano-1,2-diylo)bis[oksy(metyloetano-2,1-diylu)] (pl)
C&L Inventory
diakrylan glikolu tripropylenowego (pl)
C&L Inventory
TPGDA (pl)
C&L Inventory
tripropylenglykol-diakrylát (cs)
C&L Inventory
tripropylenglykoldiakrylat (no)
C&L Inventory
διακρυλικό (1-μεθυλ-1,2-αιθανοδιυλο)δις[οξυ(μεθυλ-2,1-αιθανοδιύλιο)] (el)
C&L Inventory
2-Propenoic acid, 1,1'-[(1-methyl-1,2-ethanediyl)bis[oxy(methyl-2,1-ethanediyl)]] ester
Other
(1-methyl-1,2-ethanediyl)bis[oxy(methyl-2,1-ethanediyl)]diacrylate
C&L Inventory
1-[(1-{[1-(prop-2-enoyloxy)propan-2-yl]oxy}propan-2-yl)oxy]propan-2-yl prop-2-enoate
C&L Inventory
1-[2-(2-prop-2-enoyloxypropoxy)propoxy]propan-2-yl prop-2-enoate
C&L Inventory
1-methyl-1,2-ethanediyl)bis[oxy(methyl-2,1-ethanediyl)] diacrylate
C&L Inventory
2-[2-(2-prop-2-enoyloxypropoxy)propoxy]propyl prop-
C&L Inventory
2-[2-(2-prop-2-enoyloxypropoxy)propoxy]propyl prop-2-enoate
C&L Inventory
2-Propenoic acid 3-{(1 or 2)-methyl-2-[(1 or 2)-methyl-2-(2-propenoyloxy)-ethoxy]-ethoxy}-3-oxopropyl ester
Registration dossier
2-Propenoic acid, (1-methyl-1,2-ethanediyl)bis[oxy(methyl-2,1-ethanediyl)] ester
C&L Inventory
2-Propenoic acid,1,1'-[(1-methyl-1,2-ethanediyl)bis[oxy(methyl-2,1-ethanediyl)]] ester
C&L Inventory
2-{2-[2-(acryloyloxy) -1-methylethoxy]-1-methylethoxy}-1-methylethyl acrylate
C&L Inventory
2-{2-[2-(acryloyloxy)-1-methylethoxy]-1-methylethoxy}-1-methylethyl acrylate
C&L Inventory, Registration dossier
[(1-methyl-1,2-ethanediyl)bis[oxy(methyl-2,1-ethanediyl)] diacrylate
Registration dossier
Tri(propylene glycol) diacrylate
C&L Inventory
TRIPROPYLENE GLYCOL DIACRYLATE
C&L Inventory, Registration dossier
Tripropylene Glycol Diacrylate (stabilized with MEHQ)
C&L Inventory
Tripropyleneglycol diacrylate
Registration dossier
2-Propenoic acid, (1-methyl-1,2-ethanediyl)bis[oxy(methyl-2,1- ethanediyl)] ester (9CI)
Registration dossier
2-Propenoic acid, (1-methyl-1,2-ethanediyl)bis[oxy(methyl-2,1-ethanediyl)] ester (9CI)
Registration dossier
AgiSyn 2815
Registration dossier
Aronix M 220
Registration dossier
Chemlink 51
Registration dossier
EM223
Registration dossier
ETERCURE DR-A801
C&L Inventory
Etermer 223
Registration dossier
GM62A00(TPGDA)
Registration dossier
Kayarad TPGDA
Registration dossier
Miramer M220
Registration dossier
NK Ester APG 200
Registration dossier
PHOTOMER 4061
Registration dossier
Sartomer 306
Registration dossier
Setacure AM 553
Registration dossier
SR 306
Registration dossier
Tripropylene glycol diacrylate (TPGDA)
Registration dossier
Tripropylenglykoldiacrylat
Registration dossier
106912-45-2
Deleted CAS number
Other
108137-10-6
Deleted CAS number
Other
123233-05-6
Deleted CAS number
Other
126968-23-8
Deleted CAS number
Other
131455-28-2
Deleted CAS number
Other
153316-73-5
Deleted CAS number
Other
1557040-15-9
Deleted CAS number
Other
160995-24-4
Deleted CAS number
Other
193898-52-1
Deleted CAS number
Other
203514-07-2
Deleted CAS number
Other
42978-66-5
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other
607-249-00-X
Index number
C&L Inventory
83045-02-7
Deleted CAS number
Other
89190-98-7
Deleted CAS number
Other

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 1 study submitted
  • 1 study processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [1]
C Odour
Other (100%) [1]
C Substance type
Organic (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Liquid (100%)

Melting/freezing point

Study results
  • 2 studies submitted
  • 1 study processed
R Melting / freezing point
-20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Boiling point

Study results
  • 3 studies submitted
  • 1 study processed
R Boiling point
120 °C @ 101.325 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Density

Study results
  • 2 studies submitted
  • 1 study processed
R Density
1.022 - 1.04 g/cm³ @ 20 - 40 °C [2]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
1.04

Vapour pressure

Study results
  • 3 studies submitted
  • 1 study processed
R Vapour pressure
0.004 Pa @ 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Vapour pressure
0.004 Pa @ 20 °C

Partition coefficient

Study results
  • 3 studies submitted
  • 1 study processed
R Log Pow
2 @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Water solubility

Study results
  • 1 study submitted
  • 1 study processed
R Water solubility (mass/vol.)
4 g/L @ 20 °C and pH 5.4 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Water solubility
4 g/L @ 20 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 2 studies submitted
  • 1 study processed
R Flash point
153 °C @ 101.325 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Flash point at 101 325 Pa
153 °C

Auto flammability

Study results
  • 2 studies submitted
  • 1 study processed
R Autoflammability / self-ignition
214 °C @ 100 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Flammability

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 3
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Non flammable (100%)

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 1 study submitted
  • 1 study processed
R dynamic viscosity (in mPa s)
6.85 - 15.1 [2]
R kinematic viscosity (in mm²/s)
6.7 - 14.5 [2]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Dynamic viscosity at 20 °C
15.1 mPa.s

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 1 study submitted
  • 1 study processed
R Dissipation half life (DT50)
5.68 h [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Hydrolysis

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in soil

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water - screening tests

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Adsorption/desorption

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Study results
  • 1 study submitted
  • 1 study processed
R H - (pressure) m³/mol
0 Pa m³/mol @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Distribution modelling

Study results
  • 1 study submitted
  • 1 study processed
% Distribution in Media:
R Air 4.2 % [1]
R Water 93.8 % [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers

No summary exists for this scientific endpoint

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 7.3 µg/L (1)
Intermittent releases (freshwater) 730 µg/L (1)
Marine water 700 ng/L (1)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 100 mg/L (1)
Sediment (freshwater) 33 µg/kg sediment dw (1)
Sediment (marine water) 3 µg/kg sediment dw (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil 2.43 µg/kg soil dw (1)
Hazard for Predators
Secondary poisoning -

Short–term toxicity to fish

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
LC50 (4 days) 4.6 - 10 mg/L [1]
LC100 (4 days) 10 mg/L [1]
NOEC (4 days) 2.15 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
EC50 (48 h) 89 mg/L [1]
EC0 (48 h) 63 mg/L [1]
EC100 (48 h) 125 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
EC50 (72 h) 65.9 mg/L [1]
EC10 (72 h) 6.6 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
EC50 (30 min) 1 g/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Sediment toxicity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 2.94 mg/m³ repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: Low hazard (no threshold derived)
Acute /short term: Low hazard (no threshold derived)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 1.7 mg/kg bw/day repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: Medium hazard (no threshold derived)
Acute /short term: High hazard (no threshold derived)
EYE Exposure
Low hazard (no threshold derived)
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: - -
Acute /short term: - -
Local Effects
Long-term: - -
Acute /short term: - -
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: - -
Acute /short term: - -
Local Effects
Long-term: - -
Acute /short term: - -
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: - -
Acute /short term: - -
EYE Exposure
-

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Acute toxicity

Study results
oral
  • 5 studies submitted
  • 2 studies processed
P/RResults
LD50 2 000 - 5 000 mg/kg bw (rat) [2]

Type of Study provided
oral
Studies with data
Key study 1 1
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 2 studies submitted
  • 2 studies processed
P/RResults
LC0 (7 h) 545 - 410 000 µg/m³ air (rat) [2]

inhalation
Studies with data
Key study 1 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 2 studies submitted
  • 2 studies processed
P/RResults
LD50 2 000 - 3 650 mg/kg bw (rabbit) [2]

dermal
Studies with data
Key study 1 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other 2
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
No adverse effect observed Discriminating dose 2 000 mg/kg bw
Dermal route:
No adverse effect observed Discriminating dose 2 000 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 11 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1 1
Supporting study 3
Weight of evidence
Other 6
Data waiving
no waivers
Study data: eye
  • 9 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 1
Supporting study 2
Weight of evidence 4
Other 2
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
No adverse effect observed (not irritating)
Eye
Adverse effect observed (irritating)
Respiratory
No study available

Sensitisation

Study results
Study data: skin
  • 13 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study
Supporting study 1
Weight of evidence 4 5
Other 2 1
Data waiving
no waivers
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
Adverse effect observed (sensitising)

Repeated dose toxicity

Study results
Study data: oral
  • 1 study submitted
  • 1 study processed
P/RResults
NOAEL (rat): 250 mg/kg bw/day [1]

Type of Study provided
Study data: oral
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: inhalation
  • 0 studies submitted
  • 0 studies processed

No data available

Study data: inhalation
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 4 studies submitted
  • 1 study processed
P/RResults
NOAEL (rat): 20 - 200 mg/kg bw/day [3]

Study data: dermal
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route - systemic effects:
Adverse effect observed NOAEL 250 mg/kg bw/day (subacute, rat)
Dermal route - local effects:
Adverse effect observed NOAEL 200 µg/cm² (subchronic, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 7 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 2 2
Supporting study
Weight of evidence 3
Other
Data waiving
no waivers
Study data: in vivo
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to reproduction

Study results
Study data: reproduction
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Study data: developmental
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 1 1
Supporting study 1 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Effect on fertility
Oral route:
No adverse effect observed NOAEL 750 mg/kg bw/day (subacute, rat)

Neurotoxicity

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant