- About Us
- Who we are
- The way we work
- Partners and networks
- Jobs
- Procurement
- Regulations
- REACH
- CLP
- Biocidal Products Regulation
- Understanding BPR
- Upcoming deadlines
- Approval of active substances
- Authorisation of biocidal products
- Technical equivalence
- In situ generated active substances
- Annex I amendment
- Product-types
- Active substances and suppliers
- BPR Legislation
- Treated articles
- Data sharing
- Chemical similarity check service
- Prior Informed Consent Regulation
- Enforcement
- Appeals
- Substituting hazardous chemicals
- Nanomaterials
- Addressing Chemicals of Concern
- Substances of potential concern
- Registry of Intentions
- Authorisation
- Restriction
- Harmonised classification and labelling
- Biocidal Products Regulation
- Information on Chemicals
- Registered substances
- Annex III inventory
- Pre-registered substances
- EC Inventory
- Dossier Evaluation decisions
- Substance evaluation - CoRAP
- Information on Candidate List substances in articles table
- C&L Inventory
- Biocidal Active Substances
- Biocidal Products
- Chemicals subject to PIC
- Transitional Measures
- Information from the Existing Substances Regulation (ESR)
- PBT/vPvB assessments under the previous EU chemicals legislation
- Chemicals in our Life
- CLP Pictograms
- What about animal testing?
- Use chemicals safely at work
- Which chemicals are of concern?
- Are there safer alternatives?
- How can I use chemicals safely?
- Hot topics
- Why are chemicals important?
- Who is responsible for chemical safety?
- How European legislation on chemicals improves our lives
- Why are nanomaterials important?
- Support
- Guidance
- Getting started
- Q&As Support
- Testing methods and alternatives
- Webinars
- Dossier Submission Tools
- Manuals
- REACH-IT
- Registration Process
- PPORD
- Notifying substances in articles
- Submitting downstream user notification of authorised uses
- Submitting a downstream user report for unsupported uses
- Submitting a downstream user report for classification differences
- How to submit and update your C&L notification
- Requesting an alternative chemical name in mixtures
- IUCLID
- CHESAR
- SPC Editor
- R4BP 3
- ePIC
- ECHA Cloud Services
- National Helpdesks
- Practical examples of exposure scenarios
- Small and Medium-sized Enterprises (SMEs)
- Registration
- Your registration obligations
- How to characterise and identify your substance
- What you need to submit
- What you need to consider for your business
- Finding your co-registrants
- Working together
- What information you need
- How to avoid unnecessary testing on animals
- Strategy for gathering your data
- Creating your registration dossier
- Submitting your registration dossier
- From submission to decision
- Practical examples – REACH registration
- Substance identification
- Authorisation
- Substances of very high concern identification
- How to apply for authorisation
- Are you affected by authorisation?
- Develop an application strategy
- Start preparing your application
- Notify ECHA and request a pre-submission information session
- Finalise your application
- Submit your application
- Engage during the opinion development
- Fulfil your obligations
- Submit a review report if you still need to use the substance
- Restriction
- Submission of CLH dossiers
- Socio-economic analysis in REACH
- How to improve your dossier
- Mixture classification
QSAR Toolbox
The Toolbox is a software application intended to be used by governments, chemical industry and other stakeholders in filling gaps in (eco)toxicity data needed for assessing the hazards of chemicals. The Toolbox incorporates information and tools from various sources into a logical workflow. Crucial to this workflow is grouping chemicals into chemical categories.
The seminal features of the Toolbox are:
- Identification of relevant structural characteristics and potential mechanism or mode of action of a target chemical.
- Identification of other chemicals that have the same structural characteristics and/or mechanism or mode of action.
- Use of existing experimental data to fill the data gap(s).
Examples with the OECD QSAR Toolbox
The illustrative examples promote the use of the OECD QSAR Toolbox for the 2018 deadline. Part 1, an introductory note, provides background information on the OECD QSAR Toolbox including general considerations. Part 2 contains case studies for selected substances.
Route: .live1