QSAR Toolbox
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Support
- Getting started
- Guidance
- Q&As Support
- Testing methods and alternatives
- Webinars
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Dossier Submission Tools
- Manuals
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REACH-IT
- Registration Process
- PPORD
- Notifying substances in articles
- Submitting downstream user notification of authorised uses
- Submitting a downstream user report for unsupported uses
- Submitting a downstream user report for classification differences
- How to submit and update your C&L notification
- Requesting an alternative chemical name in mixtures
- Joint Submission Member
- IUCLID
- CHESAR
- SPC Editor
- R4BP 3
- ePIC
- ECHA Cloud Services
- Interact Portal
- EUSES
- National Helpdesks
- Practical examples of exposure scenarios
- Practical examples of chemical safety reports
- Small and Medium-sized Enterprises (SMEs)
- Recommendations to registrants
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Registration phases
- 1. Your registration obligations
- 2. Finding your co-registrants
- 3. Get organised with your co-registrants
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4. What information you need
- Information requirements: 1 to 10 tonnes per year
- Information requirements: 10 to 100 tonnes per year
- Information requirements: 100 to 1000 tonnes per year
- Information requirements: 1000 tonnes or above per year
- Adaptations to the standard information requirements
- How to avoid unnecessary testing on animals
- Strategy for gathering your data
- 5. Creating your registration dossier
- 6. Submitting your registration dossier
- 7. Keeping your dossier up to date
- Substance identification
- Restriction
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Authorisation
- Substances of very high concern identification
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How to apply for authorisation
- Are you affected by authorisation?
- Develop an application strategy
- Start preparing your application
- Teleconference Based Information Sessions
- Teleconference based information sessions - terms and conditions of use
- Submission windows
- Notify ECHA and request a teleconference based information session
- Finalise your application
- Formats for applications for authorisation
- Submit your application
- Engage during the opinion development
- Fulfil your obligations
- Evaluating applications
- Previous events on appliction for authorisation
- Partners service for applicants
- Information on applying for authorisation by Member States and industry organisations
- Ask ECHA about authorisation applications
- Submit a review report if you still need to use the substance
- Simplified applications for authorisation for legacy spare parts
- Socio-economic analysis in REACH
- Submission of CLH dossiers
- How to improve your dossier
- QSAR Toolbox
- Mixture classification
- UK withdrawal from the EU
- ECHA accounts and EU Login
- Technical completeness check
QSAR Toolbox
The Toolbox is a software application intended to be used by governments, chemical industry and other stakeholders in filling gaps in (eco)toxicity data needed for assessing the hazards of chemicals. The Toolbox incorporates information and tools from various sources into a logical workflow. Crucial to this workflow is grouping chemicals into chemical categories.
The seminal features of the Toolbox are:
- Identification of relevant structural characteristics and potential mechanism or mode of action of a target chemical.
- Identification of other chemicals that have the same structural characteristics and/or mechanism or mode of action.
- Use of existing experimental data to fill the data gap(s).
Examples with the OECD QSAR Toolbox
The illustrative examples promote the use of the OECD QSAR Toolbox for the 2018 deadline. Part 1, an introductory note, provides background information on the OECD QSAR Toolbox including general considerations. Part 2 contains case studies for selected substances.
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