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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Description of key information

The acute toxicity of 7PPD to Daphnia magna was investigated in a static test according to EPA-660/3-75-009. After 48 hours of exposure an EC50 of 0.2 mg/L (nominal) was determined.

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
0.2 mg/L

Additional information

Short-term tests have been performed with 7PPD as well as with other similar PPDs yielding EC50-values in the range of 0.2 to 1.7 mg/L. The result of the study performed with 4-HDPA (0.69 mg/L) is within this range.  N-(1,4 -dimethylpentyl)-N'-phenylbenzene-1,4 -diamine (7PPD) is hydrolytically unstable at pH 7 and p-Hydroquinone CAS 123 -31 -9 was identified as the most sensitive (secondary) hydrolysis product. The lowest effect value in acute tests was found for p-Hydroquinone (0.134 mg/L) which is close to the values for the PPDs (0.2 to 1.9 mg/L) and 4-HDPA (0.69 mg/L). p-Hydroquinone is a secondary hydrolysis product of 7PPD, athough having the lowest effect concentration this value was not chosen as key value as the hydrolysis from 7PPD to p-Hydroquinone is rather slow.