Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: - | CAS number: -
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
The animal and vegetable cells are formed mainly by proteins, which constitute more than the half of the dry weight of the cell. These components and their degradation products are constantly present in the animal and human diet and in the environment. These components are involved in natural metabolic pathways.
After ingestion, proteins are hydrolyzed in the gastrointestinal tract by proteolytic enzymes derived from the pancreas resulting in the release of dipeptides, tripeptides and free amino acids. Digestion is further enhanced by proteases, such as aminopeptidase N, that are located in the plasma membrane of the intestinal cells. Single amino acids, as well as di- and tripeptides, are transported into the intestinal cells from the lumen and subsequently released into the blood for absorption by other tissues. The final digestion products are then used by the cells for the biosynthesis of new specific proteins, or they can then undergo further amino acid catabolism, where they are utilized as an energy source.
Key value for chemical safety assessment
- Bioaccumulation potential:
- no bioaccumulation potential
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
