3-(heptyloxy)propane-1,2-diol

Water solubility

Administrative data

Endpoint:

water solubility

Remarks:

(critical micelle concentration)

Type of information:

experimental study

Adequacy of study:

key study

Study period:

31 March 2020 - 12 May 2020

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

test procedure in accordance with generally accepted scientific standards and described in sufficient detail

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2020

Report date:

2020

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

other: ISO 4311 'Anionic and non-ionic surface active agents — Determination of the critical micellization concentration — Method by measuring surface tension with a plate, stirrup or ring'

Version / remarks:

1979

Deviations:

no

Test guideline 2

Qualifier:

according to guideline

Guideline:

other: EC A.5 'Surface Tension'

Version / remarks:

2008

Deviations:

no

Test guideline 3

Qualifier:

according to guideline

Guideline:

other: OECD 115 'Surface Tension of Aqueous Solutions'

Version / remarks:

1995

Deviations:

no

Principles of method if other than guideline:

The Critical Micelle Concentration (CMC) was determined by measuring the surface tension of test item solutions at different test item concentrations. For surface active substances which form micelles in solution, the surface tension decreases with increasing concentration until the CMC is reached. At concentrations above the CMC, the surface tension remains constant.

GLP compliance:

yes

Type of method:

other: Surface tension measurements using the OECD harmonized ring method.

Test material

Test material information

Constituent 1

Reference substance name:

3-(heptyloxy)propane-1,2-diol

Cas Number:

10305-39-2

Molecular formula:

C10H22O3

IUPAC Name:

3-(heptyloxy)propane-1,2-diol

Test material form:

liquid

Details on test material:

Physical Description: Clear slightly yellow liquid
Storage Conditions: At room temperature protected from light
Stability at higher temperatures: Yes, maximum temperature: 90°C, maximum duration: 120 minutes

Results and discussion

Water solubility

Key result

Water solubility:

3 552 mg/L

Temp.:

20 °C

Remarks on result:

other: critical micelle concentration

Any other information on results incl. tables

Table: Surface tension of substance solutions at different concentrations

Sample	Concentration C [mg/L]	Log C	Surface tension [mN/m]
1	200.67	2.3	56.32
2	500.00	2.7	46.60
3	2031.1	3.3	30.53
4	5987.5	3.8	24.41
5	7996.7	3.9	24.40
6	15042	4.2	24.40

Five measurements were performed for each test concentration until equilibrium was reached (results for each measurement are in the study report).

Applicant's summary and conclusion

Conclusions:

The critical micelle concentration of the substance was determined to be 3552 mg/L.

Executive summary:

The critical micelle concentration (CMC) of the substance was determined by measuring the surface tension of solutions at six different substance concentrations according to a method based on ISO 4311.

The surface tension measurements were performed according to the OECD harmonized ring method (according to EC A.5 and OECD 115). The measured surface tensions were plotted against the lograithms of the concentrations.Trendline y1 was obtained from the data of concentrations 200.67, 500.00 and 2031.1 mg/L. Trendline y2 was obtained from the mean surface tension of the filtered test solutions at nominal test item concentrations of 5987.5, 7996.7 and 15042 mg/L. The log C at the intersection of both lines is regarded as the log CMC and was calculated to be 3.55. From this the critical micelle concentration (CMC) of the substance was calculated to be 3552 mg/L.