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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Additional toxicological data

Currently viewing:

Administrative data

Endpoint:
additional toxicological information
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Evaluation of in vitro vs. in vivo methods for assessment of dermal absorption of organic flame retardants: a review
Author:
Abdallah M A-E et al
Year:
2015
Bibliographic source:
Enrironment Internation 74, 13-22, 2015
Reference Type:
publication
Title:
Organophosphate and phthalate esters in air and settled dust - a multi-location indoor study
Author:
Bergh C et al
Year:
2011
Bibliographic source:
Indoor Air 21, 67-76, 2011
Reference Type:
publication
Title:
Organophosphorus flame retardants (PFRs) and plasticizers in house and car dust and the influence of electronic equipment
Author:
Brandsma SH et al
Year:
2014
Bibliographic source:
Chemosphere, 2014, in press
Reference Type:
publication
Title:
Concentrations of organophosphate esters and brominated flame retardants in German indoor dust samples
Author:
Brommer S et al
Year:
2012
Bibliographic source:
J Environ Monit 14, 2482-2487, 2012
Reference Type:
publication
Title:
Distribution patterns of brominated, chlorinated, and phosphorus flame retardants with particle size in indoor and outdoor dust and implications for human exposure
Author:
Cao Z et al
Year:
2014
Bibliographic source:
Environmental Science & Technology, 2014, online
Reference Type:
publication
Title:
Differences in the seasonal variation of brominated and phosphorus flame retardants in office dust
Author:
Cao Z et al
Year:
2014
Bibliographic source:
Environmental International 65, 100-106, 2014
Reference Type:
publication
Title:
Occurrence of a broad range of legacy and emerging flame retardants in indoor environments in Norway
Author:
Cequier E et al
Year:
2014
Bibliographic source:
Environmental Science & Technology 48, 6827-6835, 2014
Reference Type:
publication
Title:
Analytical aspects for the determination of organophosphate flame retardants in indoor dust samples by GC-EI-MS
Author:
Dirtu AC et al
Year:
2010
Bibliographic source:
Organohalogen Compounds 72, 714-717, 2010
Reference Type:
publication
Title:
After the PBDE phase-out: a broad suite of flame retardants in repeat house dust samples from California
Author:
Dodson RE et al
Year:
2012
Bibliographic source:
Environmental Science & Technology, 2012, online
Reference Type:
publication
Title:
A review of chamber experiments for determining specific emission rates and investigating migration pathways of flame retardants
Author:
Rauert C et al
Year:
2014
Bibliographic source:
Atmospheric Environment 82, 44-55, 2014

Materials and methods

Type of study / information:
analysis and measurement of organophosphorus flame retardants (including TCPP) in indoor dust samples or polyurethane foam, calculated body burden, exposure assessment, metabolite levels in urine samples or human breast milk, dermal absorption

Test material

Constituent 1
Chemical structure
Reference substance name:
1-chloropropan-2-yl bis(2-chloropropyl) phosphate; bis(1-chloropropan-2-yl) 2-chloropropyl phosphate; tris(1-chloropropan-2-yl) phosphate; tris(2-chloropropyl) phosphate
EC Number:
807-935-0
Cas Number:
1244733-77-4
Molecular formula:
C9H18Cl3O4P
IUPAC Name:
1-chloropropan-2-yl bis(2-chloropropyl) phosphate; bis(1-chloropropan-2-yl) 2-chloropropyl phosphate; tris(1-chloropropan-2-yl) phosphate; tris(2-chloropropyl) phosphate

Results and discussion

Applicant's summary and conclusion