Clorofene

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

6 July 2006 to 15 August 2006

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Deviations:

not specified

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Deviations:

not specified

GLP compliance:

yes (incl. QA statement)

Remarks:

Ministerium für Umwelt und Naturschutz, Landwirtschaft und Verbraucherschutz, Düsseldorf, Nordrhein-Westfalen, Germany

Type of method:

flask method

Water solubility:

0.082 g/L

Conc. based on:

test mat.

Loading of aqueous phase:

0.71 g/L

Incubation duration:

72 h

Temp.:

10 °C

pH:

7

Water solubility:

0.084 g/L

Conc. based on:

test mat.

Loading of aqueous phase:

0.692 g/L

Incubation duration:

48 h

Temp.:

10 °C

pH:

6.9

Water solubility:

0.083 g/L

Conc. based on:

test mat.

Loading of aqueous phase:

0.687 g/L

Incubation duration:

24 h

Temp.:

10 °C

pH:

7

Key result

Water solubility:

0.117 g/L

Conc. based on:

test mat.

Loading of aqueous phase:

0.699 g/L

Incubation duration:

72 h

Temp.:

20 °C

pH:

7

Water solubility:

0.118 g/L

Conc. based on:

test mat.

Loading of aqueous phase:

0.734 g/L

Incubation duration:

48 h

Temp.:

20 °C

pH:

7.1

Water solubility:

0.117 g/L

Conc. based on:

test mat.

Loading of aqueous phase:

0.702 g/L

Incubation duration:

24 h

Temp.:

20 °C

pH:

7.1

Water solubility:

0.198 g/L

Conc. based on:

test mat.

Loading of aqueous phase:

0.726 g/L

Incubation duration:

72 h

Temp.:

30 °C

pH:

7.2

Water solubility:

0.201 g/L

Conc. based on:

test mat.

Loading of aqueous phase:

0.717 g/L

Incubation duration:

48 h

Temp.:

30 °C

pH:

7.2

Water solubility:

0.198 g/L

Conc. based on:

test mat.

Loading of aqueous phase:

0.709 g/L

Incubation duration:

24 h

Temp.:

30 °C

pH:

7.1

Individual and Final Results – Water Solubility

Test at 10 °C	Flask 1	Flask 2	Flask 3	Mean value
Water solubility of Chlorophene	0.0817g/L	0.0840g/L	0.0833g/L	0.0830 g/L
pH-value	7.0	6.9	7.0	----

Test at 20 °C	Flask 1	Flask 2	Flask 3	Mean value
Water solubility of Chlorophene	0.117g/L	0.118g/L	0.117g/L	0.117g/L
pH-value	7.0	7.1	7.1	----

Testat 30 °C	Flask 1	Flask 2	Flask 3	Mean value
Water solubility of Chlorophene	0.198g/L	0.201g/L	0.198g/L	0.199 g/L
pH-value	7.2	7.2	7.1	----

      NOTE: Preliminary test at 20 °C: 0.12 g/L

 

Conclusion:

A temperature dependence of the solubility of Chlorophene was observed. Between 10 °C and 30 °C an increase of the solubility in all test solutions from 0.08 g/L to 0.2 g/L was detected.

 

Description of key information

Water solubility is 0.0830 g/L at 10 ºC, 0.117 g/L at 20 ºC, and 0.199 g/L at 30 ºC (EU A.6, flask method).

Key value for chemical safety assessment

Water solubility:

0.117 g/L

at the temperature of:

20 °C