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EC number: 500-204-4
CAS number: 68334-05-4
No toxic effects up to the limit of water solubility (< 1 mg/L) for Danio rerio (ISO/DIS 10229-1), read-across .
As no valid study is available for assessing the chronic toxicity to
fish of Fatty acids, C18-unsatd., dimers, 2-ethylhexylesters (CAS No.
68334-05-4), in accordance to Regulation (EC) No. 1907/2006 Annex XI,
1.5 Grouping of substances, a read-across to the structurally related
substance Fatty acids, C18-unsatd., dimers, hydrogenated (CAS No.
68783-41-5) was conducted. The read across is justified due to a) the
structural similarity of the substances and b) similar physico-chemical
properties resulting in a similar environmental fate and ecotoxicity
profile. Further justification is given within the endpoint summary 6.1
and within the category justification section 13.
The study with Fatty acids, C18-unsatd., dimers, hydrogenated (CAS No.
68783-41-5) was performed according to ISO/DIS 10229-1. During the
28-day long-term toxicity study with the freshwater fish Danio rerio (Marshall,
1994) no effects on the average fish weight at the concentrations tested
(0.2 and 1.0 mg/L) were observed and a NOEC of ≥ 0.85 mg/L (measured
concentration) was determined. Thus, no effects up to the limit of the
water solubility (< 0.52 mg/L) of the tested substance were observed.
Thus, based on the above mentioned results, and due to the structural
similarities and a consistent ecotoxicological/environmental fate
profile of the substances, as are explained with in the overall endpoint
summary in IUCLID chapter 6.1, it can be concluded that no chronic
toxicity to fish is expected for Fatty acids, C18 -unsatd., dimers,
hydrogenated (CAS No. 68783 -41 -5).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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