Registration Dossier

Administrative data

Description of key information

The key skin sensitisation study, a reliable adjuvant study conducted according to OECD 406, found that the test material (100% in corn oil) applied via intradermal and epidermal routes, and using a sodium dodecyl sulphate solution to produce mild irritation prior to epidermal treatment, failed to induce a sensitisation response when challenged with 20% and 50% in corn oil. An earlier challenge using the neat material generated responses believed to indicate irritation in both the test and control groups.

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

The key skin sensitisation study (Notox, 1999), a study of reliability 1, was the only study available for this endpoint.

Respiratory sensitisation

Endpoint conclusion
Endpoint conclusion:
no study available

Justification for classification or non-classification

Based in reliable in vivo data, D6 is not classified as a skin sensitiser according to Regulation (EC) No. 1272/2008.

No data are available regarding respiratory sensitisation.