Registration Dossier
Registration Dossier
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EC number: 201-766-0 | CAS number: 87-69-4
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
- Simple salts (like calcium tartate) can be entered into the system and modeled by neutralizing the compounds (remove the salt, replace with a hydrogen atom) as the salts are typically treated as spectator ions
- we can consider compounds and dissociation at environmental conditions
- logKow for calcium tartrate and tartaric acid are similar (-1.46 vs -1.002)
- moreover, since logKow of calcium tartrate is lowest than logKow o tartaric acid, the estimated toxicity is too conservative.
- According to column 2 of REACH Annex IX, the study does not need to be conducted since tartaric acid and its salts are not toxic to fish.
- Predicted long term toxiciy to fish (FISH 30-d ChV) for tartaric acid is 43.141 g/L. Even if the predictions were performed on tartaric acid it is valid also for calcium tartrate, since:the properties and toxicity of a small number of organic salts (like Ca) are well documented in the environmental literature
-The requirement to present data for endpoints on fish early life stage toxicity test, fish short term toxicity test on embryo and sac-fry, and fish juvenile growth test is not proposed by the registrant.
LC50 (Fish, 14 day, ECOSAR) = 488 g/L used as supporting study
ChV (Fish, 30 day, ECOSAR) = 43,141 M/L used as supporting study
ChV (Fish (SW), 14 day, ECOSAR) = 13,137 M/L used as supporting study
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 43.141 g/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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