Registration Dossier
Registration Dossier
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EC number: 200-663-8 | CAS number: 67-66-3
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
Tests compliant or similar to guideline-studies on the bioconcentration of chloroform are available for different species of freshwater fish.
Key value for chemical safety assessment
- BCF (aquatic species):
- 13
Additional information
All tests were carried out in flow-through systems exposing fish to concentrations of 0.1 to 1 mg/L. The results of the Japanese bioconcentration study (MITI 1992) carried out in accordance with the OECD guideline No. 305 indicate low bioconcentration of chloroform after 42 days, and the bioconcentration factors are between 1.4 and 13. The test carried out by Anderson and Lustry (1980) with four species of freshwater fish had much shorter exposure times. Equilibrium was reached in three out of four species and bioconcentration factors were similar to those of the Japanese study: 1.6 to 10.4. These tests also demonstrated that quick depuration can be expected to take place within 24 hours after cease of exposure.
In conclusion, the highest bioconcentration factor for freshwater fish is 13, which will be considered in the risk assessment.
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