Registration Dossier
Registration Dossier
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EC number: 219-397-9 | CAS number: 2431-50-7
Toxicity to microorganisms
Administrative data
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Guideline study, basic data given
Data source
Referenceopen allclose all
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 989
- Report date:
- 1989
- Reference Type:
- secondary source
- Title:
- 2,3,4-TRICHLORO-1-BUTENE
- Author:
- ECB
- Year:
- 2 000
- Bibliographic source:
- ECB IUCLID dataset
- Reference Type:
- secondary source
- Title:
- 2,3,4-TRICHLORO-1-BUTENE - CAS No: 2431-50-7
- Author:
- OECD
- Year:
- 1 993
- Bibliographic source:
- Screening Information Data Set (SIDS) of OECD High Production Volume Chemicals Programme, (1993)
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 2,3,4-trichlorobut-1-ene
- EC Number:
- 219-397-9
- EC Name:
- 2,3,4-trichlorobut-1-ene
- Cas Number:
- 2431-50-7
- Molecular formula:
- C4H5Cl3
- IUPAC Name:
- 2,3,4-trichlorobut-1-ene
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- no
- Details on test solutions:
- directly weighted into the test vessels
Test organisms
- Test organisms (species):
- activated sludge
- Details on inoculum:
- - Laboratory culture: yes, laboratory treatment plant
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 3 h
Test conditions
- Nominal and measured concentrations:
- Nominal concentrations: 100, 180, 320, 560, 1000, 10000 mg/L
- Details on test conditions:
- TEST MEDIUM / WATER PARAMETERS
- Source/preparation of medium: according to guideline (nutrient medium: ISO 8192-1986) - Reference substance (positive control):
- yes
- Remarks:
- 3,5-dichlorphenol
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 3 h
- Dose descriptor:
- EC10
- Effect conc.:
- 59.7 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Remarks:
- respiration rate
- Duration:
- 3 h
- Dose descriptor:
- EC50
- Effect conc.:
- 394 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Remarks:
- respiration rate
- Duration:
- 3 h
- Dose descriptor:
- other: EC5
- Effect conc.:
- 35 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Remarks:
- respiration rate
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
