Registration Dossier
Registration Dossier
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EC number: 941-798-9 | CAS number: -
Endpoint summary
Administrative data
Description of key information
A bibliographic researches and in silico evaluations have been performed to characterize the toxicological profile of the UVCB substance.
Each component has been evaluated. When sufficient information on the components were not found with the literature research, the component has been evaluated by in silico methods.
Key value for chemical safety assessment
Acute toxicity: via oral route
Link to relevant study records
- Endpoint:
- acute toxicity: oral
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Guideline:
- other: REACH Guidance on QSARs R.6
- GLP compliance:
- no
- Specific details on test material used for the study:
- The SMILE of each identified component of the UVCB substance was used as input for the model.
- Species:
- rat
- Key result
- Dose descriptor:
- LD50 cut-off
- Effect level:
- 5 000 mg/kg bw
- Remarks on result:
- other: negative predicted value
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- The query structure is predicted to fall within GHS category V in the Acute Rat Oral toxicity test in silico.
- Endpoint:
- acute toxicity: oral
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Guideline:
- other: REACH Guidance on QSARs R.6
- GLP compliance:
- no
- Specific details on test material used for the study:
- The SMILE of each identified component of the UVCB substance was used as input for the model.
- Species:
- rat
- Key result
- Dose descriptor:
- LD50 cut-off
- Effect level:
- 5 000 mg/kg bw
- Based on:
- test mat.
- Remarks on result:
- other: negative predicted value
- Interpretation of results:
- Category 5 based on GHS criteria
- Conclusions:
- The QSAR results show that all constituents of the tested UVCB substance are not classified for acute toxicity oral in rat.
Referenceopen allclose all
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- LD50
- Value:
- > 2 000 mg/kg bw
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
