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EC number: 259-627-5 | CAS number: 55406-53-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Adsorption / desorption
Administrative data
Link to relevant study record(s)
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1989-08-08 to 1990-10-29
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- other: U. S. EPA Pesticide Assessment Guidelines Subdivision N, Section 163-1
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: Agriculture Canada Trade Memorandum T-1-255
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- batch equilibrium method
- Media:
- soil
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL RADIOLABELED
- Source and lot/batch No.of test material: NBN/l/77/1
RADIOLABELLING INFORMATION
- Specific activity: 108 µCi/mg
SOURCE OF TEST MATERIAL NON-LABELED
- Source and lot/batch No.of test material: N.J. L7-93
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: room temperature - Radiolabelling:
- yes
- Test temperature:
- 22 +/- 1 °C
- Analytical monitoring:
- yes
- Details on sampling:
- - Concentrations: 100, 50 10, 1 µg/mL
- Sampling interval: three desorption steps were performed on those soils receiving the highest concentration - Matrix no.:
- #1
- Matrix type:
- sandy loam
- % Clay:
- 10
- % Silt:
- 24
- % Sand:
- 66
- % Org. carbon:
- 0.75
- pH:
- 6
- CEC:
- 4.9 meq/100 g soil d.w.
- Matrix no.:
- #2
- Matrix type:
- sand
- % Clay:
- 4
- % Silt:
- 4
- % Sand:
- 92
- % Org. carbon:
- 0.46
- pH:
- 5.8
- CEC:
- 2 meq/100 g soil d.w.
- Matrix no.:
- #3
- Matrix type:
- loam
- % Clay:
- 14
- % Silt:
- 40
- % Sand:
- 46
- % Org. carbon:
- 1.6
- pH:
- 5.9
- CEC:
- 10 meq/100 g soil d.w.
- Matrix no.:
- #4
- Matrix type:
- silty clay
- % Clay:
- 40
- % Silt:
- 46
- % Sand:
- 14
- % Org. carbon:
- 1.3
- pH:
- 5.6
- CEC:
- 21.1 meq/100 g soil d.w.
- Matrix no.:
- #5
- Matrix type:
- sand
- % Clay:
- 3
- % Silt:
- 5
- % Sand:
- 92
- % Org. carbon:
- 2
- pH:
- 3.9
- CEC:
- 3.5 meq/100 g soil d.w.
- Details on matrix:
- COLLECTION AND STORAGE
- Soil preparation: 2 mm sieved - Details on test conditions:
- TEST CONDITIONS
- initial concentrations: 100, 50, 10, 1 µg/L
TEST SYSTEM
- Type, size and further details on reaction vessel: 50 mL glass centrifuge tubes, capped with Teflon-lined screw caps
- Solution/Soil ratio: 5:1
- Number of reaction vessels/concentration (replicates): 2
- Measuring equipment: HPLC UV and LSC detector
- Test performed in closed vessels: yes - Duration:
- 2 h
- Temp.:
- 22 °C
- Remarks:
- for respective concentrations
- Duration:
- 2 h
- Temp.:
- 22 °C
- Remarks:
- for respective concentrations
- Computational methods:
- Log-log scales were used to plot the amount of test item adsorbed versus equilibrium concentration in terms of the empirical Freundlich adsorption equation (Weber, 1986):
X/M = K C^N
or in the log transformation form:
log (X/M) = log K + N(log C)
where X is the amount of test item adsorbed (µg), M is the mass of soil (g), C is the equilibrium concentration (µg/mL), and log K and N are constants representing the intercept of the isotherm and the slope, respectively.
Log-log scales also were used to plot the amount of test item adsorbed versus equilibrium mole fraction in a modified Freundlich equation format (Bowman, 1982):
Sy = Kmf * Z^N
or in the log transformation form:
log Sy = log Kmf + N log Z
where Kmf = S at Z = 1.0 and is designated in this fashion to avoid confusion with the K value in the traditional Freundlich isotherm. The K, value is only an empirical regression constant and has no real value as a means of comparing adsorption since it is evaluated Z = 1.0 (pure pesticide). Instead of using K values as a measure of relative adsorption, adsorption values [Sy] are determined at a common Z value within the range of the data, where Y = log Z. This subscript, Y, is a simple way of quickly identifying the log concentration (log mole fraction) at which the relative adsorption comparisons were made. - Key result
- Sample No.:
- #1
- Type:
- Koc
- Value:
- 90.1 dimensionless
- pH:
- 6
- Temp.:
- 22 °C
- Matrix:
- loam
- Key result
- Sample No.:
- #2
- Type:
- Koc
- Value:
- 309 dimensionless
- pH:
- 5.8
- Temp.:
- 22 °C
- Matrix:
- sand
- Key result
- Sample No.:
- #3
- Type:
- Koc
- Value:
- 61 dimensionless
- pH:
- 5.9
- Temp.:
- 22 °C
- Matrix:
- loam
- Key result
- Sample No.:
- #4
- Type:
- Koc
- Value:
- 89.2 dimensionless
- pH:
- 5.6
- Temp.:
- 22 °C
- Matrix:
- clay
- Key result
- Sample No.:
- #5
- Type:
- Koc
- Value:
- 123 dimensionless
- pH:
- 3.9
- Temp.:
- 22 °C
- Matrix:
- sand
- Adsorption and desorption constants:
- Kads: 0.676 - 2.46
Kdes: 3.43 - 31.3 - Recovery of test material:
- Material balance values ranged from 87.66 to 99.11 % for the soils used.
- Duration:
- 2 h
- % Adsorption:
- > 7.99 - < 37.9
- Transformation products:
- not measured
- Validity criteria fulfilled:
- yes
- Conclusions:
- The test item was adsorbed in moderate amounts by the soils used in this study with adsorption K values ranging from 61.0 to 309. Test item adsorption did not appear to be highly correlated with soil organic matter content, clay content, or cation exchange capacity. Test item was readily degraded to propargyl butyl carbamate in suspensions from the Evesboro, Blackoar, and Mexico soils. Differences in relative adsorption between soils may have been related to differences in the extent of test item degradation
- Executive summary:
The test item adsorption/desorption by soils was investigated using radioisotope techniques via the batch equilibrium (slurry) method (Weber, 1986). The soils used in this study were a Hanford sandy loam (#1), a Centhan sand (#2), a Blackoar loam (#3), a Mexico silty clay (#4), and an Evesboro sand (#5). Initial test item concentrations were approximately 100, 50, 10, and 1 µg/mL, and the solution: soil ratio was 5:1. Three desorption steps were performed on those soils receiving the highest initial test item concentration.Adsorption and desorption isotherms are presented using two sets of units. The first set of data (µg Basis) is presented with amount adsorbed (µg/g) plotted versus equilibrium concentration (µg/mL). Kads and Kdes values were calculated with this data to permit comparison of relative adsorption. The second set of data (mole Basis) is presented with amount adsorbed (mole/g) plotted versus equilibrium mole fraction (unitless). Using this format, relative adsorption values (Sy) are compared at a common solution mole fraction. The subscript Y is a simple means of quickly identifying the log concentration (log mole fraction) at which the relative adsorption comparisons were made. For this study, Y = -6. Test item was adsorbed in moderate amounts by soils with Kads values ranging from 0.676 to 2.46 and S-6 values ranging from 1.45e-07 to 3.01e-08. Test item adsorption did not appear to be directly related to either soil organic matter content, clay content, or cation exchange capacity. Adsorption and desorption K values were variable indicating that factors other than organic carbon content determine the extent of test item adsorption. Bound C residues were quantified using soil oxidation and liquid scintillation techniques. Material balance values ranged from 87.66 to 99.11% further validating adsorption and desorption calculations.
Reference
Description of key information
The test item was adsorbed in moderate amounts by the soils used in this study with adsorption K values ranging from 61.0 to 309. Test item adsorption did not appear to be highly correlated with soil organic matter content, clay content, or cation exchange capacity. Test item was readily degraded to propargyl butyl carbamate in suspensions from the soils. Differences in relative adsorption between soils may have been related to differences in the extent of test item degradation. As a worst case assumption Koc value of 309 is applied as key value.
Key value for chemical safety assessment
- Koc at 20 °C:
- 309
Additional information
The test item adsorption/desorption by soils was investigated using radioisotope techniques via the batch equilibrium (slurry) method (Weber, 1986). The soils used in this study were a Hanford sandy loam (#1), a Centhan sand (#2), a Blackoar loam (#3), a Mexico silty clay (#4), and an Evesboro sand (#5). Initial test item concentrations were approximately 100, 50, 10, and 1 µg/mL, and the solution: soil ratio was 5:1. Three desorption steps were performed on those soils receiving the highest initial test item concentration.Adsorption and desorption isotherms are presented using two sets of units. The first set of data (µg Basis) is presented with amount adsorbed (µg/g) plotted versus equilibrium concentration (µg/mL). Kads and Kdes values were calculated with this data to permit comparison of relative adsorption. The second set of data (mole Basis) is presented with amount adsorbed (mole/g) plotted versus equilibrium mole fraction (unitless). Using this format, relative adsorption values (Sy) are compared at a common solution mole fraction. The subscript Y is a simple means of quickly identifying the log concentration (log mole fraction) at which the relative adsorption comparisons were made. For this study, Y = -6.Test item was adsorbed in moderate amounts by soils with Kads values ranging from 0.676 to 2.46 and S-6 values ranging from 1.45e-07 to 3.01e-08. Test item adsorption did not appear to be directly related to either soil organic matter content, clay content, or cation exchange capacity. Adsorption and desorption K values were variable indicating that factors other than organic carbon content determine the extent of test item adsorption. Bound C residues were quantified using soil oxidation and liquid scintillation techniques. Material balance values ranged from 87.66 to 99.11% further validating adsorption and desorption calculations.
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