Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Workers - Hazard via inhalation route

Systemic effects

Long term exposure
Hazard assessment conclusion:
no hazard identified
Acute/short term exposure
Hazard assessment conclusion:
no hazard identified
DNEL related information

Local effects

Long term exposure
Hazard assessment conclusion:
DNEL (Derived No Effect Level)
Value:
9.3 mg/m³
Most sensitive endpoint:
irritation (respiratory tract)
DNEL related information
DNEL derivation method:
other: Assessment based on the IOEL for hydrochloric acid (8 mg/m3 (8 h TWA) in Commission Directive 2000/39/EC).
Overall assessment factor (AF):
1
Dose descriptor:
other: IOEL
AF for dose response relationship:
1
Justification:
Not required as assessment based on OEL.
AF for differences in duration of exposure:
1
Justification:
Not required as assessment based on OEL.
AF for interspecies differences (allometric scaling):
1
Justification:
Not required as assessment based on OEL.
AF for other interspecies differences:
1
Justification:
Not required as assessment based on OEL.
AF for intraspecies differences:
1
Justification:
Not required as assessment based on OEL.
AF for the quality of the whole database:
1
Justification:
Not required as assessment based on OEL.
AF for remaining uncertainties:
1
Justification:
Not required as assessment based on OEL.
Acute/short term exposure
Hazard assessment conclusion:
DNEL (Derived No Effect Level)
Value:
17.5 mg/m³
Most sensitive endpoint:
irritation (respiratory tract)
DNEL related information
DNEL derivation method:
other: based on 15-minute STEL for HCl
Overall assessment factor (AF):
1
AF for dose response relationship:
1
Justification:
DNEL based on IOEL for HCl
AF for interspecies differences (allometric scaling):
1
Justification:
DNEL based on IOEL for HCl
AF for other interspecies differences:
1
Justification:
DNEL based on IOEL for HCl
AF for intraspecies differences:
1
Justification:
DNEL based on IOEL for HCl
AF for the quality of the whole database:
1
Justification:
DNEL based on IOEL for HCl
AF for remaining uncertainties:
1
Justification:
DNEL based on IOEL for HCl

Workers - Hazard via dermal route

Systemic effects

Long term exposure
Hazard assessment conclusion:
no hazard identified
Acute/short term exposure
Hazard assessment conclusion:
no hazard identified
DNEL related information

Local effects

Long term exposure
Hazard assessment conclusion:
high hazard (no threshold derived)
Most sensitive endpoint:
skin irritation/corrosion
Acute/short term exposure
Hazard assessment conclusion:
high hazard (no threshold derived)
Most sensitive endpoint:
skin irritation/corrosion

Workers - Hazard for the eyes

Local effects

Hazard assessment conclusion:
high hazard (no threshold derived)

Additional information - workers

General Population - Hazard via inhalation route

Systemic effects

Long term exposure
Hazard assessment conclusion:
no hazard identified
Acute/short term exposure
Hazard assessment conclusion:
no hazard identified
DNEL related information

Local effects

Long term exposure
Hazard assessment conclusion:
no hazard identified
Acute/short term exposure
Hazard assessment conclusion:
no hazard identified
DNEL related information

General Population - Hazard via dermal route

Systemic effects

Long term exposure
Hazard assessment conclusion:
no hazard identified
Acute/short term exposure
Hazard assessment conclusion:
no hazard identified
DNEL related information

Local effects

Long term exposure
Hazard assessment conclusion:
no hazard identified
Acute/short term exposure
Hazard assessment conclusion:
no hazard identified

General Population - Hazard via oral route

Systemic effects

Long term exposure
Hazard assessment conclusion:
no hazard identified
Acute/short term exposure
Hazard assessment conclusion:
no hazard identified
DNEL related information

General Population - Hazard for the eyes

Local effects

Hazard assessment conclusion:
no hazard identified

Additional information - General Population

There are no consumer uses of silicon tetrachloride, therefore it is not possible for the local effects caused by the hydrolysis product, HCl, to occur. In the case of exposure via the environment, silicon tetrachloride does not exist due to rapid hydrolysis to HCl and monosilicic acid. Exposure of the general population could potentially be to condensed monosilicic acid, polysilicic acid (SAS), for which a 90-day oral repeated dose, reproductive and developmental toxicity studies are available to show that adverse systemic effects are not expected. Hence, the overall conclusion 'no hazard identified' for the general population for all routes and durations of exposure. It is also of note that monosilicic acid and polysilicic acid are naturally occurring substances which are ubiquitous in the environment.