Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 224-235-5 | CAS number: 4259-15-8
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
In a Magnusson-Kilgman Guinea pig maximization test, 20 Dunkin-Hartley strain albino Guinea pigs were treated with 5% w/v test substance (Costello BA and Gilman MR, 1982). Scores of zero in all test animals were obtained at all points examined. The test substance does not appear to be a sensitizer in the albino guinea pig. In accordance to Directive 67/548/EEC and EU CLP (Regulation (EC) No. 1272/2008), this substance does not meet the criteria for classification as a skin sensitizer.
Migrated from Short description of key information:
The test material is not a skin sensitizer.
Respiratory sensitisation
Endpoint conclusion
- Additional information:
- Migrated from Short description of key information:
No data available for respiratory sensitization.
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
