Registration Dossier
Registration Dossier
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EC number: 215-133-1 | CAS number: 1304-56-9
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (sensitising)
- Additional information:
No OECD guideline studies available. Only one human study was found reliable (Curtis, 1951). This study did not demonstrate a sensitising effect of BeO while other beryllium substances were sensitising. Although the study is relatively old and with a limited cohort it clearly demonstrates a difference between BeO and the other Be salts. It should also be mentioned that the other Be salts caused "spontaneous flare-ups" in controls with no prior exposure to Be compounds while this was not observed with BeO.
Migrated from Short description of key information:
Sensitisation was not observed in beryllium workers challenged with BeO
Respiratory sensitisation
Endpoint conclusion
- Additional information:
- Migrated from Short description of key information:
No studies available
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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