Bromoacetyl bromide

Guidance on Safe Use

First-aid measures

Description of necessary first-aid measures

General information:

Pay attention to self-protection. Remove victims from hazardous area. Immediately remove soiled or soaked clothing and remove it to a safe distance. Keep victim warm, in a stabilized position and covered. Do not leave the victim unattended. Place patients who are unconscious but breathing in the stabilized lateral position.

Inhalation:

Potential for exposure by inhalation if aerosols or mists are generated. Move to fresh air. With labored breathing: Provide with oxygen. Consult a doctor immediately. If the casualty is not breathing: Perform mouth-to-mouth resuscitation, notify emergency physician immediately.

Skin Contact:

Wash off affected area immediately with plenty of water for at least 15 minutes. Get medical attention if any discomfort continues.

Eye contact:

With eye held open, thoroughly rinse immediately with plenty of water for at least 10 minutes. Consult an ophthalmologist immediately if the symptoms persist. When dealing with caustic substances, notify emergency physician immediately (key words: burns in eye).

Ingestion:

Rinse mouth. Immediately give large quantities of water to drink. Seek medical advice. When dealing with caustic substances, notify emergency physician immediately.

Personal Protection for First-aid Responders:

No data available.

Most important symptoms and effects, both acute and delayed

Symptoms:

Irritation of skin and mucous membranes. Corrosive. Daze. Headache, vertigo, somnolence (sleepiness), nausea. Health injuries may be delayed.

Hazards:

Strongly irritating to corrosive. Harmful in contact with skin and if swallowed. Vapours may cause drowsiness and dizziness.

Indication of immediate medical attention and special treatment needed
Treatment:

The initial focus is only on the local action, characterized by quickly progressing deep tissue damage. In the eye, caustic/ irritating and harmful liquids cause, depending on the intensity of exposure, various levels of irritation, destruction, and ablation of the epithelium of the conjunctiva and cornea, corneal clouding, edema and ulcerations. Danger! Possible loss of eyesight! Superficial irritations and damage up to ulcerations and scarring develop on the skin. After accidental absorption in the body, the pathology and clinical findings are dependent on the kinetics of the substance (quantity of absorbed substance, the absorption time, and the effectiveness of early elimination measures (first aid)/ excretion - metabolism). A specific action of the substance is unknown. In case of substances with high water solubility, irritations up to formation of necrosis in the upper respiratory tract may result after inhalation of caustic/ irritating aerosols and mists. The initial focus is on the local action: signs of irritation of the respiratory tract such as coughing, burning behind the sternum, tears, burning in the eyes or nose. There is a risk of pulmonary edema!

Fire-fighting measures

Extinguishing media

Suitable extinguishing media:

Dry powder. Carbon Dioxide.

Unsuitable extinguishing media:

Do NOT use water jet. Alcohol resistant foam.

Special hazards arising from the substance or mixture:

Reacts violently with water and foam. Hazard-determining flue gases might develop in case of fire: Carbon Monoxide. Carbon Dioxide. Hydrogen bromide. Under certain conditions of combustion traces of other toxic substances cannot be excluded.

Advice for firefighters

Special fire-fighting procedures:

Water used to extinguish fire should not enter drainage systems, soil or stretches of water. Contaminated extinguishing water must be treated at a suitable disposal plant in accordance with waste management laws. In case of fire, remove the endangered containers and bring to a safe place, if this can be done safely. Fire residues should be disposed of in accordance with the regulations. Use water spray to cool unopened containers. Keep unauthorized personnel away.

Special protective equipment for fire-fighters:

In case of fire: full protective suit and wear a self contained respiratory apparatus.

Accidental release measures

Personal precautions, protective equipment and emergency procedures:

Keep unauthorized personnel away.

For non-emergency personnel:

No data available.

For emergency responders:

No data available.

Environmental Precautions:

Observe regulations on prevention of water pollution (check, dam up, cover up). Do not allow entrance in sewage water, soil, stretches of water, drainage systems, surface water. If the product contaminates rivers and lakes or drains inform respective authorities.

Methods and material for containment and cleaning up:

Pick up mechanically with a suitable material and collect in a suitable container. Pack and label wastes like the pure substance. Do not detach label from the delivery containers prior to disposal. Disposal according to local authority regulations.

Reference to other sections:

For personal protection see Exposure controls/personal protection.

Handling and storage

Precautions for safe handling

Technical measures (e.g. Local and general ventilation):

The substance must be handled under strictly controlled conditions in accordance with Article 17/18 of the REACH regulation. Provide for installation of emergency shower and eye bath. Refill and handle product only in closed system. Leak detection recommended. Do not add wastewater to a biological wastewater treatment plant. Dispose of waste gases in a suitable incineration plant. Minimization of emissions by means of suitable technical measures such as flanges and valves with low leakage rates, recirculation of vapours. All precautionary measures indicated have to be observed.

Safe handling advice:

All precautionary measures indicated have to be observed. Risk assessment and risk monitoring of all work places required. Health, Safety and Emergency Management System recommended. Regular safety training is a must. Written approval necessary in case of non-routine jobs, e.g. maintenance activities. The personal protective equipment used must meet the requirements of Regulation (EU) 2016/425 and amendments (CE certification). It should be defined in the work place in the form of a risk analysis according to Regulation (EU) 2016/425 and amendments. Use permissible in closed systems only. Handle and transfer product in closed systems only (gas displacement device). Ensure that apparatus and pipelines are free from leaks. Do not ventilate into the open. Suitable loading and unloading device required.

Contact avoidance measures:

No data available.

Conditions for safe storage, including any incompatibilities

Safe storage conditions:

Protect from sunlight, warmth and heat. In order to ensure due transportation, make certain that stacks are of the correct height, containers are securely fastened so as not to fall off, and labelled according to the regulations. In the event of internal transportation, already-opened containers are to be kept closed in order to avoid spillage. Normal measures for preventive fire protection. Store in the original receptable, keeping this tightly sealed, under cool and dry conditions.

Safe packaging materials:

No data available.

Storage Class:

8 A: Combustible corrosive substances

Transport information

Land transport (UN RTDG/ADR/RID)

UN number:

UN 2513

Shipping information

Proper shipping name and description:

BROMOACETYL BROMIDE

Packing group:

Packing group II: Substances presenting medium danger

Labels:

8

SpecialProvisions

Inland waterway transport (UN RTDG/ADN(R))

UN number:

UN 2513

Shipping information

Proper shipping name and description:

BROMOACETYL BROMIDE

Packing group:

Packing group II: Substances presenting medium danger

Labels:

8

Remarks

Marine transport (UN RTDG/IMDG)

UN number:

UN 2513

Shipping information

Proper shipping name and description:

BROMOACETYL BROMIDE

Packing group:

Packing group II: Substances presenting medium danger

EmS code:

F-A

S-B

Labels:

8

Marine pollutant

Special provisions / remarks

Remarks:

Clear of living quarters. Stow "separated from" alkalis.

Air transport (UN RTDG/ICAO/IATA)

UN number:

UN 2513

Shipping information

Proper shipping name and description:

Bromoacetyl bromide

Packing group:

Packing group II: Substances presenting medium danger

Labels:

8

Remarks

SpecialProvisions

Exposure controls / personal protection

Exposure controls

Appropriate Engineering Controls:

The substance must be handled under strictly controlled conditions in accordance with Article 17/18 of the REACH regulation. Provide for installation of emergency shower and eye bath. Refill and handle product only in closed system. Leak detection recommended. Do not add wastewater to a biological wastewater treatment plant. Dispose of waste gases in a suitable incineration plant. Minimization of emissions by means of suitable technical measures such as flanges and valves with low leakage rates, recirculation of vapours. All precautionary measures indicated have to be observed.

Individual protection measures, such as personal protective equipment

Eye/face protection:

Safety glasses with side-shields conforming to EN166 or Accidental release measures goggles.

Hand Protection:

Material: Nitrile.

Glove thickness: 0.2 mm

Guideline: DIN EN 374

Material: Nitrile/Chloroprene

Glove thickness: 0.65 mm

Guideline: DIN EN 374

Additional Information: Accidental release measures

Skin and Body Protection:

Select materials and equipment for physical protection depending on the concentration and volume of hazardous substances and the workplace involved.

Respiratory Protection:

Accidental release measures Suitable filter: A, code colour brown

Hygiene measures:

Do not eat, drink, smoke, or sniff while at work. Wash your hands and/or face before breaks and before termination of work. Avoid contact with eyes, skin, and clothing. Take off contaminated clothing and wash it before reuse. Preventive skin protection is recommended. Use barrier cream regularly.

Environmental Controls:

In some cases, exhaust air scrubbers, filters or technical changes to the processing plant will be required in order to decrease emissions to acceptable values. The environmental regulations on the control and monitoring of environmental exposures are to be observed.

Stability and reactivity

Reactivity:

No dangerous reaction known under conditions of normal use.

Chemical Stability:

Stable under normal conditions.

Possibility of hazardous reactions:

No hazardous reactions are known if properly handled and stored.

Conditions to avoid:

Water. Exposure to water vapour. Avoid all contact with metal.

Incompatible Materials:

Water. Alcohols. Alkalies. Strong oxidizing agents. Strong bases.

Hazardous Decomposition Products:

Carbon Monoxide. Carbon Dioxide. Hydrogen bromide.

Disposal considerations

Waste treatment methods

General information:

No data available.

Disposal methods:

Strictly controlled conditions during disposal or treatment to air, wastewater and waste. Do not add wastewater to a biological wastewater treatment plant. Disposal according to local authority regulations. Pack and label wastes like the pure substance. Do not detach label from the delivery containers prior to disposal.

Contaminated Packaging:

Do not reuse empty containers and dispose of in accordance with the regulations issued by the appropriate local authorities.