Summary of Classification and Labelling
Harmonised classification - Annex VI of Regulation (EC) No 1272/2008 (CLP Regulation)
General Information
Index Number EC / List no. CAS Number International Chemical Identification
615-005-00-9 247-714-0 26447-40-5 methylenediphenyl diisocyanate

ATP Inserted / Updated: CLP00/ATP01
CLP Classification (Table 3)
Classification Labelling Specific Concentration limits, M-Factors, Acute Toxicity Estimates (ATE) Notes
Hazard Class and Category Code(s) Hazard Statement Code(s) Hazard Statement Code(s) Supplementary Hazard Statement Code(s) Pictograms, Signal Word Code(s)
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
Eye Irrit. 2; H319: C ≥ 5 %
Resp. Sens. 1; H334: C ≥ 0,1 %
STOT SE 3; H335: C ≥ 5 %
Skin Irrit. 2; H315: C ≥ 5 %
Note 2
Note C
Eye Irrit. 2 H319 H319
Skin Sens. 1 H317 H317
Acute Tox. 4 * H332 H332
STOT SE 3 H335 H335
Resp. Sens. 1 H334 H334
Carc. 2 H351 H351
STOT RE 2 * H373 ** H373 **

Signal Words Pictograms
Danger
GHS07
Exclamation mark
GHS08
Health hazard
Seveso III Data
Disclaimer: Please note that some of the substances covered by the Seveso Directive can belong to more than one Seveso categories. It will be up to the users to decide whether their substance or mixture fall in one or in more of these classification categories depending on the tonnage bands and the concentrations.
Please also note that ECHA is not an authority for the Seveso Directive and that the Seveso categorisation below is provided for information only. The Seveso III Directive (Directive 2012/18/EU repealing Directive 96/82/EC (Seveso II) from 1 June 2015) is the only authentic legal reference and that the information in this inventory does not constitute legal advice. For further information on Seveso, please ask your national authority.

Seveso Data
Seveso Substance Seveso Categories
Nee
Notified classification and labelling
General Information
EC / List no.
Name CAS Number
247-714-0 Methylenediphenyl diisocyanate 26447-40-5

Notified classification and labelling according to CLP criteria
Classification Labelling Specific Concentration limits, M-Factors Notes Classification affected by Impurities / Additives

Additional Notified Information

Number of Notifiers

Joint Entries

Hazard Class and Category Code(s) Hazard Statement Code(s) Hazard Statement Code(s) Supplementary Hazard Statement Code(s) Pictograms, Signal Word Code(s)
Skin Irrit. 2 H315 H315 GHS07
GHS08
GHS06
Dgr
Note 2
Note C
441 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 2 H330 H330
Resp. Sens. 1 H334 H334
STOT SE 3 H335 (other:unknown) H335
Carc. 2 H351 H351
STOT RE 2 H373 (other:unknown) H373
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
Skin Irrit. 2; : C ≥ 5 %
Eye Irrit. 2; : C ≥ 5 %
Note 2
Note C
State/Form
117 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 4 H332 H332
Resp. Sens. 1 H334 H334
STOT SE 3 H335 H335
Carc. 2 H351 H351
STOT RE 2 H373 H373
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
Skin Irrit. 2; : C ≥ 5 %
Eye Irrit. 2; : C ≥ 5 %
Resp. Sens. 1; : C ≥ .1 %
STOT SE 3; : C ≥ 5 %
Note 2
Note C
State/Form
103 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 4 H332 H332
Resp. Sens. 1 H334 H334
STOT SE 3 H335 H335
Carc. 2 H351 H351
STOT RE 2 H373 H373
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
Eye Irrit. 2; : C ≥ 5 %
Skin Irrit. 2; : C ≥ 5 %
Note 2
Note C
State/Form
93 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 4 H332 H332
Resp. Sens. 1 H334 H334
STOT SE 3 H335 (other:-) H335
STOT SE 3 H335 H335
Carc. 2 H351 H351
STOT RE 2 H373 H373
STOT RE 2 H373 (other:-) H373
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
Eye Irrit. 2; : C ≥ 5 %
STOT SE 3; : C ≥ 5 %
Resp. Sens. 1; : C ≥ .1 %
Skin Irrit. 2; : C ≥ 5 %
State/Form
87 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 4 H332 H332
Resp. Sens. 1 H334 H334
STOT SE 3 H335 (not available) H335
STOT SE 3 H335 (other:not avail...) H335
Carc. 2 H351 H351
STOT RE 2 H373 (not available) H373
STOT RE 2 H373 (other:not avail...) H373
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
STOT SE 3; : C ≥ 5 %
Skin Irrit. 2; : C ≥ 5 %
Eye Irrit. 2; : C ≥ 5 %
Resp. Sens. 1; : C ≥ .1 %
Note 2
Note C
State/Form
77 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 4 H332 H332
Resp. Sens. 1 H334 H334
STOT SE 3 H335 (other:-) H335
Carc. 2 H351 H351
STOT RE 2 H373 (other:-) H373
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
State/Form
71 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 4 H332 H332
Resp. Sens. 1 H334 H334
Carc. 2 H351 H351
STOT SE 3 H370 (other:unknown) H370
STOT RE 2 H373 (other:unknown) H373
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
Skin Irrit. 2; : C ≥ 5 %
Eye Irrit. 2; : C ≥ 5 %
STOT SE 3; : C ≥ 5 %
Resp. Sens. 1; : C ≥ .1 %
State/Form
61 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 4 H332 H332
Resp. Sens. 1 H334 H334
STOT SE 3 H335 H335
Carc. 2 H351 H351
STOT RE 2 H373 H373
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
38 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 4 H332 H332
Resp. Sens. 1 H334 H334
STOT SE 3 H335 H335
Carc. 2 H351 H351
STOT RE 2 H373 H373
Not Classified               37  
Skin Irrit. 2 H315 H315 EUH204
GHS08
GHS06
Dgr
37 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 2 H330 H330
Resp. Sens. 1 H334 H334
STOT SE 3 H335 (other:Not avail...) H335
STOT SE 3 H335 (Not available) H335
Carc. 2 H351 H351
STOT RE 2 H373 (Not available) H373
STOT RE 2 H373 (other:Not avail...) H373
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
Resp. Sens. 1; : C ≥ .1 %
Eye Irrit. 2; : C ≥ 5 %
Skin Irrit. 2; : C ≥ 5 %
STOT SE 3; : C ≥ 5 %
State/Form
32 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 4 H332 H332
Resp. Sens. 1 H334 H334
STOT SE 3 H335 (not specified) H335
Carc. 2 H351  
STOT RE 2 H373 (not specified)  
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
Skin Irrit. 2; : C ≥ 5 %
Eye Irrit. 2; : C ≥ 5 %
Resp. Sens. 1; : C ≥ .1 %
STOT SE 3; : C ≥ 5 %
28 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 4 H332 H332
Resp. Sens. 1 H334 H334
STOT SE 3 H335 (other:Respirato...) H335
Carc. 2 H351 H351 (Suspected of ca...)
STOT RE 2 H373 (other:Respirato...) H373 (May cause damag...)
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
State/Form
25 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 4 H332 H332
Resp. Sens. 1 H334 H334
STOT SE 3 H335 (Affected Organs) H335
STOT SE 3 H335 (other:Affected ...) H335
STOT RE 2 H373 (other:Affected ...) (inhalation) H373
STOT RE 2 H373 (Affected Organs) (inhalation) H373
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
Skin Irrit. 2; : C ≥ 5 %
Eye Irrit. 2; : C ≥ 5 %
STOT SE 3; : C ≥ 5 %
Resp. Sens. 1; : C ≥ .1 %
Note 2
Note C
State/Form
23 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 4 H332 H332
Resp. Sens. 1 H334 H334
STOT SE 3 H335 H335
STOT SE 3 H335 (other:-) H335
Carc. 2 H351 H351
STOT RE 2 H373 H373
STOT RE 2 H373 (other:-) H373
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
Eye Irrit. 2; : C ≥ 5 %
STOT SE 3; : C ≥ 5 %
Resp. Sens. 1; : C ≥ .1 %
Skin Irrit. 2; : C ≥ 5 %
State/Form
22 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 4 H332 H332
Resp. Sens. 1 H334 H334
STOT SE 3 H335 (lungs) H335
Carc. 2 H351 H351
STOT RE 2 H373 (other:Lung) (inhalation) H373
STOT RE 2 H373 (Lung) (inhalation) H373
Skin Irrit. 2 H315 H315 EUH204
Dgr
State/Form
15 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 4 H332 H332
Resp. Sens. 1 H334 H334
STOT SE 3 H335 (lungs) (inhalation) H335
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
13 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 4 H332 H332
Resp. Sens. 1 H334 H334
STOT SE 3 H335 (other:respirato...) H335
Carc. 2 H351 H351
STOT RE 2 H373 (other:respirato...) H373
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
Skin Irrit. 2; : C ≥ 5 %
Resp. Sens. 1; : C ≥ .1 %
Eye Irrit. 2; : C ≥ 5 %
STOT SE 3; : C ≥ 5 %
Note 2
Note C
11 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 4 H332 H332
Resp. Sens. 1 H334 H334
STOT SE 3 H335 (other:Respirato...) H335
STOT SE 3 H335 (Respiratory sys...) H335
Carc. 2 H351 H351
STOT RE 2 H373 (Lungs) H373
STOT RE 2 H373 (lungs) H373
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
State/Form
10 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 4 H332 H332
Resp. Sens. 1 H334 H334
STOT SE 3 H335 (not identified) H335
STOT SE 3 H335 (other:not ident...) H335
Carc. 2 H351 H351
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
Resp. Sens. 1; : C ≥ .1 %
STOT SE 3; : C ≥ 5 %
Eye Irrit. 2; : C ≥ 5 %
Skin Irrit. 2; : C ≥ 5 %
State/Form
7 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 4 H332 H332
Resp. Sens. 1 H334 H334
STOT SE 3 H335 (other:Respirato...) H335
STOT SE 3 H335 (Respiratory sys...) H335
Carc. 2 H351 H351
STOT RE 2 H373 (not specified)  
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
STOT SE 3; : C ≥ 5 %
Eye Irrit. 2; : C ≥ 5 %
Skin Irrit. 2; : C ≥ 5 %
Resp. Sens. 1; : C ≥ .1 %
7 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 4 H332 H332
Resp. Sens. 1 H334 H334
STOT SE 3 H335 (other:-) H335
STOT SE 3 H335 H335
Carc. 2 H351 H351
STOT RE 2 H373 (other:-) H373
STOT RE 2 H373 H373
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
Resp. Sens. 1; : C ≥ .1 %
Eye Irrit. 2; : C ≥ 5 %
Skin Irrit. 2; : C ≥ 5 %
STOT SE 3; : C ≥ 5 %
Note 2
Note C
5 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 4 H332 H332
Resp. Sens. 1 H334 H334
STOT SE 3 H335 (Upper respirato...) H335
STOT SE 3 H335 (other:Upper res...) H335
Carc. 2 H351 H351
STOT RE 2 H373 (other:Upper res...) H373
STOT RE 2 H373 (Upper respirato...) H373
Skin Irrit. 2 H315 H315 (H315) GHS07
GHS08
Dgr
Note 2
Note C
5 View details
Skin Sens. 1 H317 H317 (H317)
Eye Irrit. 2 H319 H319 (H319)
Acute Tox. 4 H332 H332 (H332)
Resp. Sens. 1 H334 H334 (H334)
STOT SE 3 H335 (other:respirato...) H335 (H335)
Carc. 2 H351 H351 (H351)
STOT RE 2 H373 (other:eyes, ski...) H373 (H373)
STOT RE 2 H373 (eyes, skin, res...) H373 (H373)
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
Resp. Sens. 1; : .1 % ≤ C < 100 %
Eye Irrit. 2; : 5 % ≤ C < 100 %
Skin Irrit. 2; : 5 % ≤ C < 100 %
Note 2
Note C
3 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 4 H332 H332
Resp. Sens. 1 H334 H334
Carc. 2 H351 H351 (Suspected of ca...)
STOT RE 2 H373 (other:respirato...) H373 (May cause damag...)
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
Skin Irrit. 2; : 5 % ≤ C < 100 %
Eye Irrit. 2; : 5 % ≤ C < 100 %
STOT SE 3; : 5 % ≤ C < 100 %
Resp. Sens. 1; : .1 % ≤ C < 100 %
Note 2
Note C
3 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 4 H332 H332
Resp. Sens. 1 H334 H334
STOT SE 3 H335 (Not applicable) H335
STOT SE 3 H335 (other:Not appli...) H335
Carc. 2 H351 H351 (Suspected of ca...)
STOT RE 2 H373 (other:respirato...) H373 (May cause damag...)
Acute Tox. 4 H302   GHS07
GHS08
Dgr
State/Form
2 View details
Skin Irrit. 2 H315 H315
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 4 H332 H332
Resp. Sens. 1 H334 H334
STOT SE 3 H335 (Lung) H335
STOT SE 3 H335 (other:Lung) H335
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
Resp. Sens. 1; : C ≥ .1 %
STOT SE 3; : C ≥ 5 %
Skin Irrit. 2; : C ≥ 5 %
Eye Irrit. 2; : C ≥ 5 %
Note 2
Note C
2 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 4 H332 H332
Resp. Sens. 1 H334 H334
STOT SE 3 H335 (Respiratory sys...) H335
Carc. 2 H351 H351
STOT RE 2 H373 (Respiratory Tra...) (inhalation) H373
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
Skin Irrit. 2; : C ≥ 5 %
Resp. Sens. 1; : C ≥ .1 %
Eye Irrit. 2; : C ≥ 5 %
Note C
1 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 4 H332 H332
Resp. Sens. 1 H334 H334
  H335
Skin Irrit. 2 H315 H315 Dgr
1 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 4 H332 H332
Resp. Sens. 1 H334 H334
STOT SE 3 H335 (not specified) H335
Carc. 2 H351 H351
STOT RE 2 H373 (not specified) H373
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
Resp. Sens. 1; : .1 % < C ≤ 100 %
Skin Irrit. 2; : 5 % < C ≤ 100 %
Eye Irrit. 2; : 5 % < C ≤ 100 %
Note 2
Note C
1 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 4 H332 H332
Resp. Sens. 1 H334 H334
Carc. 2 H351 H351 (Suspected of ca...)
STOT RE 2 H373 (other:respirato...) H373 (May cause damag...)
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
1 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 4 H332 H332
Resp. Sens. 1 H334 H334
STOT SE 3 H335 (data lacking) H335
STOT SE 3 H335 (other:data lack...) H335
Carc. 2 H351 H351
STOT RE 2 H373 (other:data lack...) H373
STOT RE 2 H373 (data lacking) H373
Skin Irrit. 2 H315 H315 GHS08
GHS07
Wng
Note 2
Note C
State/Form
1 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 4 H332 H332
Resp. Sens. 1 H334 H334
STOT SE 2 H335 (not determined) H335
Carc. 2 H351 (dermal,inhalati...) H351
STOT RE 2 H373 (not determined) H373
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
State/Form
1 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 4 H332 H332
Resp. Sens. 1 H334 H334
STOT SE 3 H335 (Central System) H335
Carc. 2 H351 H351
STOT RE 2 H373 (Central system) H373
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
Skin Irrit. 2; : 5 % ≤ C < 100 %
STOT SE 3; : 5 % ≤ C < 100 %
7546; : 0 % ≤ C < 100 %
STOT RE 2; : 0 % ≤ C < 100 %
Eye Irrit. 2; : 5 % ≤ C < 100 %
Resp. Sens. 1; : .1 % ≤ C < 100 %
Note 2
Note C
1 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 4 H332 H332
Resp. Sens. 1 H334 H334
STOT SE 3 H335 H335
Carc. 2 H351 H351
STOT RE 2 H373 H373
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
7546; : 0 % ≤ C < 100 %
Eye Irrit. 2; : C ≥ 5 %
STOT RE 2; : 0 % ≤ C < 100 %
Skin Irrit. 2; : C ≥ 5 %
Resp. Sens. 1; : C ≥ .1 %
STOT SE 3; : C ≥ 5 %
Note 2
Note C
1 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 4 H332 H332
Resp. Sens. 1 H334 H334
STOT SE 3 H335 H335
Carc. 2 H351 H351
STOT RE 2 H373 H373
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
STOT SE 3; : 5 % ≤ C < 100 %
Resp. Sens. 1; : .1 % ≤ C < 100 %
Eye Irrit. 2; : 5 % ≤ C < 100 %
Skin Irrit. 2; : 5 % ≤ C < 100 %
Note 2
Note C
1 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 4 H332 H332
Resp. Sens. 1 H334 H334
STOT SE 3 H335 H335
Carc. 2 H351 H351
STOT RE 2 H373 H373
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
Skin Irrit. 2; : C ≥ 5 %
Eye Irrit. 2; : C ≥ 5 %
Resp. Sens. 1; : C ≥ .1 %
STOT SE 3; : C ≥ 5 %
Note 2
Note C
State/Form
1 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 4 H332 H332
Resp. Sens. 1 H334 H334
STOT SE 3 H335 (other:Respirato...) (inhalation) H335
Carc. 2 H351 H351
STOT RE 2 H373 (other:Unknown) (inhalation) H373
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
Skin Irrit. 2; : C ≥ 5 %
STOT SE 3; : C ≥ 5 %
Eye Irrit. 2; : C ≥ 5 %
Resp. Sens. 1; : C ≥ .1 %
Note 2
Note C
1 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 4 H332 H332
Resp. Sens. 1 H334 H334
STOT SE 3 H335 (other:-) H335
Carc. 2 H351 H351
STOT RE 2 H373 (other:respirato...) H373

Number of Aggregated Notifications: 39