Summary of Classification and Labelling
Harmonised classification - Annex VI of Regulation (EC) No 1272/2008 (CLP Regulation)
General Information
Index Number EC / List no. CAS Number International Chemical Identification
606-021-00-7 212-828-1 872-50-4 N-methyl-2-pyrrolidone
1-methyl-2-pyrrolidone

ATP Inserted / Updated: CLP00/ATP09
CLP Classification (Table 3)
Classification Labelling Specific Concentration limits, M-Factors, Acute Toxicity Estimates (ATE) Notes
Hazard Class and Category Code(s) Hazard Statement Code(s) Hazard Statement Code(s) Supplementary Hazard Statement Code(s) Pictograms, Signal Word Code(s)
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
STOT SE 3; H335: C ≥ 10 %
Eye Irrit. 2 H319 H319
STOT SE 3 H335 H335
Repr. 1B H360D *** H360D ***

Signal Words Pictograms
Danger
GHS08
Health hazard
GHS07
Exclamation mark
Seveso III Data
Disclaimer: Please note that some of the substances covered by the Seveso Directive can belong to more than one Seveso categories. It will be up to the users to decide whether their substance or mixture fall in one or in more of these classification categories depending on the tonnage bands and the concentrations.
Please also note that ECHA is not an authority for the Seveso Directive and that the Seveso categorisation below is provided for information only. The Seveso III Directive (Directive 2012/18/EU repealing Directive 96/82/EC (Seveso II) from 1 June 2015) is the only authentic legal reference and that the information in this inventory does not constitute legal advice. For further information on Seveso, please ask your national authority.

Seveso Data
Seveso Substance Seveso Categories
Nee
Notified classification and labelling
General Information
EC / List no.
Name CAS Number
212-828-1 1-methyl-2-pyrrolidone 872-50-4

Notified classification and labelling according to CLP criteria
Classification Labelling Specific Concentration limits, M-Factors Notes Classification affected by Impurities / Additives

Additional Notified Information

Number of Notifiers

Joint Entries

Hazard Class and Category Code(s) Hazard Statement Code(s) Hazard Statement Code(s) Supplementary Hazard Statement Code(s) Pictograms, Signal Word Code(s)
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
STOT SE 3; : C ≥ 10 %
State/Form
52 yes View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (other:nose) H335
Repr. 1B H360 (developmental e...) H360 (unborn child)
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
State/Form
2 yes View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (other:respirato...) (inhalation) H335
Repr. 1B H360 (May damage the ...)  
  H360D
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
Repr. 1B; : C ≥ 5 %
State/Form
842 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 H335
Repr. 1B H360 (D) H360 (D)
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
Repr. 1B; : C ≥ 5 %
State/Form
492 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (other:-) H335
STOT SE 3 H335 H335
Repr. 1B H360 (D) H360 (D)
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
STOT SE 3; : C ≥ 10 %
Repr. 1B; : C ≥ 5 %
State/Form
165 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 H335
Repr. 1B H360 (D) H360 (D)
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
STOT SE 3; : C ≥ 10 %
State/Form
133 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 H335
Repr. 1B H360 (D) H360
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
Repr. 1B; : C ≥ 5 %
STOT SE 3; : C ≥ 10 %
State/Form
90 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (other:-) H335
STOT SE 3 H335 H335
Repr. 1B H360 (D) H360 (D)
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
Repr. 1B; : C ≥ 5 %
STOT SE 3; : C ≥ 10 %
State/Form
87 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (not available) H335
STOT SE 3 H335 (other:not avail...) H335
Repr. 1B H360 (unborn child) H360
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
State/Form
71 View details
Eye Irrit. 2 H319 H319
Repr. 1B H360 H360
STOT SE 3 H370 (other:unknown) H370
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
STOT SE 3; : C ≥ 10 %
67 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (other:Respirato...) H335
Repr. 1B H360D (H360D:May damag...) H360D (May damage the ...)
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
STOT SE 3; : C ≥ 10 %
Repr. 1B; : C ≥ 5 %
State/Form
62 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 H335
Repr. 1B H360 (D) H360
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
STOT SE 3; : C ≥ 10 %
60 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (Respiratory sys...) H335
Repr. 1B H360 (D)  
  H360D
Skin Irrit. 2 H315 H315 GHS08
Dgr
STOT SE 3; : C ≥ 10 %
59 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (Not provided) H335
STOT SE 3 H335 (other:Not provi...) H335
Repr. 1B H360 H360
Skin Irrit. 2 H315 H315 GHS07
Wng
State/Form
57 View details
Eye Irrit. 2 H319 H319
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
STOT SE 3; : C ≥ 10 %
State/Form
40 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (other:-) H335
Repr. 1B H360 (D) H360
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
37 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (Not available) H335
STOT SE 3 H335 (other:Not avail...) H335
Repr. 1B H360 (Unborn child) H360
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
State/Form
36 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 H335
Repr. 1B H360 (D) H360
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
Repr. 1B; : C ≥ 5 %
STOT SE 3; : C ≥ 10 %
State/Form
35 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (not specified) H335
Repr. 1B H360  
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
STOT SE 3; : C ≥ 10 %
Repr. 1B; : C ≥ 5 %
31 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (other:Blood, ki...) H335
STOT SE 3 H335 (Blood, kidneys,...) H335
Repr. 1B H360 H360
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
State/Form
25 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (other:Affected ...) H335
STOT SE 3 H335 (Affected Organs) H335
Repr. 1B H360 (D) H360 (D)
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
24 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (Respiratory sys...) H335
STOT SE 3 H335 (other:Respirato...) H335
Repr. 1B H360 H360
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
State/Form
24 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (No data) (oral) H335
Repr. 1B H360 H360
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
STOT SE 3; : C ≥ 5 %
Repr. 1B; : C ≥ 5 %
State/Form
22 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (other:Lung) (inhalation) H335
STOT SE 3 H335 (Lung) (inhalation) H335
Repr. 1B H360 H360
Skin Irrit. 2 H315 H315 GHS08
Dgr
STOT SE 3; : C ≥ 10 %
12 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 H335
Repr. 1B H360 H360
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
11 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (Respiratory sys...) H335
Repr. 1B H360 H360
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
Repr. 1B; : C ≥ 5 %
State/Form
11 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (other:respirato...) H335
Repr. 1B H360 (H360D) H360
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
State/Form
10 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (not identified) H335
STOT SE 3 H335 (other:not ident...) H335
Repr. 1B H360 H360
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
State/Form
10 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (other:Respirato...) H335
STOT SE 3 H335 (Respiratory sys...) H335
Repr. 1B H360 (oral) (May damage the ...) H360
Repr. 1B H360 (May damage the ...) H360
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
Repr. 1B; : 5 % ≤ C ≤ 100 %
STOT SE 3; : 10 % ≤ C ≤ 100 %
yes State/Form
9 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (other:respirato...) H335
Repr. 1B H360 H360
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
STOT SE 3; : C ≥ 10 %
Repr. 1B; : C ≥ 5 %
9 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (Respiratory tra...) H335
STOT SE 3 H335 (other:Respirato...) H335
Repr. 1B H360 H360
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
STOT SE 3; : C ≥ 10 %
State/Form
8 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 H335
STOT SE 3 H335 (other:-) H335
Repr. 1B H360 (D) H360
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
STOT SE 3; : C ≥ 10 %
State/Form
8 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (other:Respirato...) H335
Repr. 1B H360D H360D
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
6 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (Respiratory tra...) H335
STOT SE 3 H335 (other:Respirato...) H335
Repr. 1B H360 H360 (D)
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
Repr. 1B; : C ≥ 5 %
State/Form
6 View details
Eye Irrit. 2 H319 H319
  H335
Repr. 1B H360 (H360D May damag...)  
Skin Irrit. 2 H315 H315 (H315) GHS07
GHS08
Dgr
5 View details
Eye Irrit. 2 H319 H319 (H319)
STOT SE 3 H335 (other:respirato...) H335 (H335)
Repr. 1B H360 (May damage the ...) H360 (May damage the ...)
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
Repr. 1B; : 5 % ≤ C < 100 %
4 View details
Eye Irrit. 2 H319 H319
Repr. 1B H360 (May damage the ...) H360 (May damage the ...)
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
4 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (other:data lack...) H335
STOT SE 3 H335 (data lacking) H335
Repr. 1B H360 H360
Skin Irrit. 2 H315 H315 GHS08
Dgr
State/Form
4 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (other:organs) H335
STOT SE 3 H335 (organs) H335
Repr. 1B H360 H360
Skin Irrit. 2 H315 H315 GHS08
Wng
3 View details
Eye Irrit. 2 H319 H319
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
Repr. 1B; : C ≥ 5 %
3 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 H335
Repr. 1B H360 (oral) (D) H360 (D)
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
Repr. 1B; : 5 % ≤ C < 100 %
STOT SE 3; : 10 % ≤ C < 100 %
3 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (Not applicable) H335
STOT SE 3 H335 (other:Not appli...) H335
Repr. 1B H360 (May damage the ...) H360 (May damage the ...)
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
State/Form
3 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (other:lung) (inhalation) H335
STOT SE 3 H335 (lung) (inhalation) H335
Repr. 1A H360 H360
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
STOT SE 3; : C ≥ 10 %
Repr. 1B; : C ≥ 5 %
State/Form
3 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (other:-) H335
Repr. 1B H360 (D) H360
Skin Irrit. 2 H315 H315 (H319: Causes se...) GHS07
Wng
2 View details
Eye Irrit. 2 H319  
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
State/Form
2 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (Lung) H335
STOT SE 3 H335 (other:Lung) H335
Repr. 1B H360 H360
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
Repr. 1B; : C ≥ 5 %
STOT SE 3; : C ≥ 10 %
2 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (other:Respirato...) H335
Repr. 1B H360 (D) H360
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
State/Form
1 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (other:ucous mem...) (dermal,oral) H335
Repr. 1B H360 H360
Repr. 1B H360 (dermal) H360
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
State/Form
1 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (Not provided) H335
STOT SE 3 H335 (other:Not provi...) H335
Repr. 1B H360 H360
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
Repr. 1B; : C ≥ 5 %
STOT SE 3; : C ≥ 10 %
State/Form
1 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (other:not avail...) H335
STOT SE 3 H335 (not available) H335
Repr. 1B H360 H360
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
1 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (other:Inhalatio...) H335
STOT SE 3 H335 (Inhalation) H335
Repr. 1B H360 H360
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
STOT SE 3; : C ≥ 10 %
Repr. 1B; : C ≥ 5 %
State/Form
1 View details
Eye Irrit. 2A H319 H319
STOT SE 3 H335 (No information ...) H335
Repr. 1B H360 (May damage the ...) H360
Skin Irrit. 2 H315   Dgr
1 View details
Eye Irrit. 2 H319  
STOT SE 3 H335 (other:not known)  
STOT SE 3 H335 (not known)  
Repr. 1B H360  
  NA
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
STOT SE 3; : C ≥ 10 %
Repr. 1B; : C ≥ 5 %
State/Form
1 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (other:unknown) H335
Repr. 1B H360 (unknown) H360 (May damage fert...)
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
Repr. 1B; : C ≥ 5 %
STOT SE 3; : C ≥ 10 %
State/Form
1 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (other:respirato...) (inhalation) H335
Repr. 1B H360 H360
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
State/Form
1 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (other:Not deter...) H335
STOT SE 3 H335 (Not determined) H335
Repr. 1A H360 (H360D: May dama...) H360
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
State/Form
1 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (other:respirato...) (inhalation) H335
Repr. 1B H360 (oral) (developmental) H360 (developmental -...)
Not Classified               1  
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
State/Form
1 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (other:Respirato...) H335
STOT SE 3 H335 (Respiratory tra...) H335
Repr. 1B H360 H360
Skin Irrit. 2 H315 H315 GHS07
Wng
State/Form
1 View details
Eye Irrit. 2 H319 H319
Acute Tox. 4 H332 H332
  H335
Skin Irrit. 2 H315 H315 GHS08
GHS07
GHS05
Wng
1 View details
Eye Dam. 1 H318 H318
STOT SE 3 H335 (other:lung) H335
STOT SE 3 H335 (lung) H335
STOT RE 1 H372 (lung) H372
STOT RE 1 H372 (other:lung) H372
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
State/Form
1 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (Not determined) H335
Repr. 1A H360 (H360D: May dama...) H360
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
Repr. 1B; : C ≥ 5 %
State/Form
1 View details
Eye Irrit. 2 H319 H319
  H335
Repr. 1A H360 (H360D May damag...)  
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
1 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (other:RTI) H335
STOT SE 3 H335 (RTI) H335
Repr. 1A H360 H360
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
STOT SE 3; : 10 % < C ≤ 100 %
Repr. 1B; : 5 % < C ≤ 100 %
State/Form
1 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (other:lung) H335
STOT SE 3 H335 (lung) H335
Repr. 1B H360 H360
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
Repr. 1B; : C ≥ 5 %
State/Form
1 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (inhalation) H335
STOT SE 3 H335 (other:-) (inhalation) H335
Repr. 1B H360 (D) H360 (D)
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
State/Form
1 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (other:Respirato...) H335
STOT SE 3 H335 (Respiratory org...) H335
Repr. 1B H360 (May damage the ...) H360
Repr. 1B H360 (oral) (May damage the ...) H360
Skin Irrit. 2 H315 H315 GHS07
GHS08
Wng
State/Form
1 View details
Eye Irrit. 2 H319 H319
Repr. 2 H361 H361
Repr. 2 H361 (oral) H361
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
Repr. 1B; : C ≥ 5 %
STOT SE 3; : C ≥ 10 %
State/Form
1 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (Respiratory tra...) (inhalation) H335
Repr. 1B H360 H360
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
Repr. 1B; : C ≥ 5 %
1 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (other:respirato...) H335
Repr. 1B H360 H360
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
STOT SE 3; : C ≥ 10 %
Repr. 1B; : C ≥ 5 %
State/Form
1 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (nose) (inhalation) H335
Repr. 1B H360 (oral) (development) H360 (D)
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
State/Form
1 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (Respiratory sys...) (inhalation,oral) H335
Repr. 1B H360 (inhalation,oral) ((Unborn child)) H360
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
State/Form
1 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (other:respirato...) (inhalation) H335
Repr. 1B H360 (360D) H360 (360D)
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
STOT SE 3; : 10 % ≤ C ≤ 100 %
1 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (other:nose) H335
Repr. 1B H360D H360D
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
STOT SE 3; : C ≥ 10 %
State/Form
1 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (other:-) H335
Repr. 1B H360 (D) H360
STOT RE 2 H373 (blood,spleen,ki...) (inhalation) H373
Skin Irrit. 2 H315 H315 GHS08
GHS07
Dgr
1 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 H335
Repr. 1B H360D H360D
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
STOT SE 3; : C ≥ 10 %
State/Form
1 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (other:-) H335
STOT SE 3 H336 H336
Repr. 1B H360 (D) H360
Asp. Tox. 1 H304 H304 GHS08
GHS07
Dgr
STOT SE 3; : C ≥ 10 %
State/Form
1 View details
Skin Irrit. 2 H315 H315
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (other:not appli...) H335
Repr. 1B H360D H360D
STOT RE 1 H372 (lungs,adrenal g...) (inhalation) H372
Skin Irrit. 2 H315 H315 GHS07
GHS08
Dgr
STOT SE 3; : C ≥ 10 %
State/Form
1 View details
Eye Irrit. 2 H319 H319
STOT SE 3 H335 (other:-) H335
Repr. 1B H360D H360D

Number of Aggregated Notifications: 78