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EC number: 421-880-6 | CAS number: 201792-73-6
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- November 11, 2009-November 21, 2011
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with generally accepted scientific standards and described in sufficient detail
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient)
- GLP compliance:
- no
- Type of method:
- shake-flask method to: flask method
- Partition coefficient type:
- octanol-water
- Analytical method:
- other: spectrophotometry UV-Vis
- Type:
- log Pow
- Partition coefficient:
- ca. -1.73
- pH:
- ca. 8.64
- Remarks on result:
- other: T n.a.
- Conclusions:
- The partition coefficient of the tested substance Acid Black 210, is logPow= -1.73
- Executive summary:
The partition coefficient n-octanol/wtaer of Acid Black 210 was assessed following EU A8, by shake flask method and spectrophotometric determination of the concentrations in water and n-octanol.
The log Pow is equal to -1.73
Reference
Table No.3 Results of determination of partition coefficient
Ratio |
Water phase |
n-octanol phase |
Pow |
log Pow |
Average |
||
c (g/L) |
Average |
c (g/L) |
Average |
||||
50/50 |
0.04516 |
0.04786 |
0.00091 |
0.00090 |
0.0202 |
-1.6937 |
-1.7250 |
50/50 |
0.05057 |
0.00089 |
0.0175 |
-1.7563 |
|||
60/30 |
0.04837 |
0.04871 |
0.00075 |
0.00068 |
0.0154 |
-1.8115 |
-1.8581 |
60/30 |
0.04904 |
0.00061 |
0.0125 |
-1.9047 |
|||
30/60 |
0.05025 |
0.05045 |
0.00127 |
0.00124 |
0.0252 |
-1.5989 |
-1.6104 |
30/60 |
0.05065 |
0.00121 |
0.0239 |
-1.6220 |
|||
Average of Powwas 0.0191; standard deviation of Powwas 0.0049.
Average of log Powwas –1.73, standard deviation of log Powwas 0.12
The partition coefficient of test substance, Acid Black 210, is: log Pow =–1.73.
Description of key information
-1.73
Key value for chemical safety assessment
- Log Kow (Log Pow):
- -1.73
- at the temperature of:
- 25 °C
Additional information
A study was performed on Acid Black 210, following EU A8 by shake flask method (Stahl, 1996). The summary available is lacking of many information and therefore the test is used as supporting test. The log Kow at 25°C is equal to -3.1.
Another study, used as key study, (Michal Bartos, 2011) was performed on Acid Black 210 according to EU method A.8. At pH 8.6 the log Kow is equal to -1.73.
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