Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 205-526-6
CAS number: 142-18-7
Readily biodegradable: 79.5% in 28 days (OECD 301B)
No experimental data evaluating the biodegradation potential of
2,3-dihydroxypropyl laurate (CAS No. 142-18-7) are available. Therefore,
a biodegradation study conducted with a structurally related category
member (Glycerides, C12-18 di- and tri-, CAS No. 91744-28-4) are used as
read-across (in accordance with Regulation (EC) No. 1907/2006, Annex XI,
1.5). Both substances are esters formed from the esterification of fatty
acids (C12 monoester and C12-18 di- and triester, respectively) and
glycerol. Even though Glycerides, C12-18 di- and tri- is an UVCB
substance, it has a high content of C12 fatty acids (40-65%) and
therefore, it is expected to give a good indication of the
biodegradation potential of 2,3-dihydroxypropyl laurate. Furthermore,
Glycerides, C12-18 di- and tri- contains longer fatty acid C-chain
lengths and a higher degree of esterification (diester and triester)
compared to that of 2,3-dihydroxypropyl laurate. These two factors are
expected to result in a reduced biodegradation potential of Glycerides,
C12-18 di- and tri- with respect to 2,3-dihydroxypropyl laurate, and
therefore it is considered a worst-case read-across.
A study evaluating the potential for ready biodegradability of
Glycerides, C12-18 di- and tri- (CAS No. 91744-28-4) is available
(Flach, 2012). The test was conducted according to OECD Guideline 301B,
under GLP conditions. Activated sludge microorganisms were exposed to
the test substance for a period of 28 days, and biodegradation followed
by measuring the CO2 production in the test vessels. After 28 days, the
test substance reached 79.5% biodegradation, and therefore, it can be
considered as readily biodegradable. The results obtained in the
toxicity control (55% biodegradation within 14 days) show that
Glycerides, C12-18 di- and tri- is not toxic to and therefore
non-inhibitory of activated sludge microorganisms activity.
Based on the results obtained for the structurally related
analogue substance (in accordance with Regulation (EC) No. 1907/2006,
Annex XI, 1.5), 2,3-dihydroxypropyl laurate can be considered as readily
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again