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Ankstesni/Rezultatai

Ankstesni/Rezultatai

Ankstesni/Rezultatai

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

 

Further information

 

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100 Items per Page
Showing 1 - 100 of 1 996 results.
Name
EC Number
CAS Number
Hazard endpoint for which vertebrate testing was proposed
Date of publication to call for available information
Deadline for submitting information
Alternatives to vertebrate testing
 
Silicon 231-130-8 7440-21-3 Subchronic toxicity (90 day): inhalation 14/02/2011 31/03/2011 Details
Tetraethyllead 201-075-4 78-00-2 Sub-chronic toxicity study (90-day) 01/07/2011 15/08/2011 Details
Fatty acids, tall-oil, compds. with diethanolamine 263-157-6 61790-66-7 Sub-chronic toxicity (90-day): oral||Note: testing proposed with Amides, C8-18 (even numbered) and C18-unsatd., N-(2-hydroxypropyl)  (EC no. 931-329-6) 03/05/2023 19/06/2023 Details
methylsilanetriyl triacetate 224-221-9 4253-34-3 Sub-chronic toxicity (90-day): oral||Note: testing proposed with [triethoxy(methyl)silane] (CAS no. 2031-67-6) 03/10/2023 17/11/2023 Details
3-{[3-(C10-16-oxy)propyl]amino}propan-1-aminium acetate 941-152-6 - Sub-chronic toxicity (90-day): oral||Note: testing proposed with 1,3-propanediamine, N-[3-((C11-14, C13-rich)oxy)propyl]-branched acetate (EC: 931-295-2) 15/07/2022 29/08/2022 Details
N-{3-[C12-14-(even numbered)-alkyloxy]propyl}propane-1,3-diamine 701-437-6 - Sub-chronic toxicity (90-day): oral|| Note: testing proposed with [1,3-propanediamine, N-[3-((C11-14, C13-rich)oxy)propyl]-branched acetate (EC no 931-295-2) 15/07/2022 29/08/2022 Details
4-tert-butylcyclohexyl acetate 250-954-9 32210-23-4 Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with cis-4-tert-butylcyclohexyl acetate 		24/02/2020 09/04/2020 Details
Tetramethylammonium hydroxide 200-882-9 75-59-2 Sub-chronic toxicity (90-day): oral
// Note: testing proposed with Tetramethylammonium chloride (EC 200-880-8)
|| Note: Link to justification in the registration dossier not given as the information is confidential 		27/01/2020 12/03/2020 Details
2,4,6,8-tetramethylcyclotetrasiloxane 219-137-4 2370-88-9
Sub-chronic toxicity (90-day): oral
-
22/11/2017
22/11/2017
08/01/2018
08/01/2017
 Details
(Z)-4-[C11-13(branched)alkylamino]-4-oxo-2-butenoic acid 701-116-0 84583-68-6 Sub-chronic toxicity (90-day): oral || Note: The previous EC number for the substance is 283-219-6. 22/06/2017 07/08/2017 Details
Octadecanoic acid, sulfonated, potassium salt 701-179-4 - Sub-chronic toxicity (90-day): oral || Note: The List number has changed. 31/01/2018 19/03/2018 Details
octyltrichlorosilane 226-112-1 5283-66-9 Sub-chronic toxicity (90-day): oral || Note: testing proposed with triethoxy(2,4,4-trimethylpentyl)silane (EC 252-558-1, CAS 35435-21-3) 25/06/2015 10/08/2015 Details
trimethoxyoctylsilane 221-338-7 3069-40-7 Sub-chronic toxicity (90-day): oral || Note: testing proposed with triethoxy(2,4,4-trimethylpentyl)silane (CAS 35435-21-3) 07/08/2015 22/09/2015 Details
Reaction mass of 4,4,13,13-tetraethoxy-3,14-dioxa-8,9-dithia-4,13-disilahexadecane and 4,4,14,14-tetraethoxy-3,15-dioxa-8,9,10-trithia-4,14-disilaheptadecane 915-748-1 - Sub-chronic toxicity (90-day): oral || Note: testing proposed with polysulfides, bis[3-(triethyoxysilyl)propyl (CAS No 211519-85-6) 25/05/2020 09/07/2020 Details
tetraethylammonium hydroxide 201-073-3 77-98-5 Sub-chronic toxicity (90-day): oral || Note: testing proposed with N,N,N-trimethylmethanaminium chloride (EC 200-880-8; CAS 75-57-0) 30/09/2015 16/11/2015 Details
2-Propyn-1-ol, reaction product with 1-2.5 moles of oxirane 941-793-1 - Sub-chronic toxicity (90-day): oral || Note: testing proposed with 2-Propyn-1-ol, compd. with methyloxirane (EC 609-530-2, CAS 38172-91-7) 17/04/2015 04/06/2015 Details
branched-nonyl 3,5,5 trimethylhexanoate 701-133-3 - Sub-chronic toxicity (90-day): oral || Note: previous EC no 609-993-0 21/05/2018 05/07/2018 Details
N,N''-propane-1,3-diylbis[N'-octadecylurea 252-667-4 35674-65-8 Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity) 29/03/2016 13/05/2016 Details
Resin acids and Rosin acids, hydrogenated, Me esters 232-476-2 8050-15-5 Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin, methyl ester (CAS RN 68186-14-1), Rosin, ethylene glycol ester (CAS RN 68512-65-2) and Rosin, triethylene glycol ester (CAS RN 8050-25-7) 02/07/2013 16/08/2013 Details
Resin acids and Rosin acids, esters with ethylene glycol 270-986-7 68512-65-2 Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin, ethylene glycol ester (CAS RN 68512-65-2) 02/07/2013 16/08/2013 Details
Resin acids and Rosin acids, reaction products with formaldehyde, potassium salt 295-855-1 92129-53-8 Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin (CAS RN 8050-09-7), Rosin, hydrogenated (CAS RN 65997-06-0), and Rosin, reaction products with formaldehyde (CAS RN 91081-53-7) 02/07/2013 16/08/2013 Details
Rosin, oligomers 500-163-2 65997-05-9 Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin (CAS RN 8050-09-7), Rosin, hydrogenated (CAS RN 65997-06-0), and Rosin, reaction products with formaldehyde (CAS RN 91081-53-7) 02/07/2013 16/08/2013 Details
Amines, C12-14-tert-alkyl, mixed sec-Bu and iso-Bu phosphates 306-227-4 96690-34-5 Sub-chronic toxicity (90-day): oral || Note: testing proposed with Amines, C11-14-branched alkyl, monohexyl and dihexyl phosphates (EC 279-632-6) || Note: Testing proposal is based on concern identified by the registrant. 23/11/2020 07/01/2021 Details
trimethoxy(2,4,4-trimethylpentyl)silane 251-995-5 34396-03-7 Sub-chronic toxicity (90-day): oral
Note: testing proposed with triethoxy(2,4,4-trimethylpentyl)silane (EC 252-558-1, CAS 35435-21-3) " 		25/06/2015 10/08/2015 Details
Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C11-17 and C17 unsatd. alkyl) derivs. and sodium hydroxide and 2-propenoic acid 946-533-0 - Sub-chronic toxicity (90-day): oral || Note: testing proposed with β-Alanine, N-(2-aminoethyl)-N-(2-hydroxyethyl)-, N-coco acyl derivs., monosodium salts (EC 298-632-7) 16/12/2020 01/02/2021 Details
Sodium 4(or 5)-methyl-1H-benzotriazolide 265-004-9 64665-57-2 Sub-chronic toxicity (90-day): oral || Note: testing proposed with Tolyltriazole (EC 249-596-6) 16/12/2020 01/02/2021 Details
(1-methylethylidene)di-4,1-phenylene tetraphenyl diphosphate,Bisphenol A Diphosphate,Bisphenol A Polyphosphate 425-220-8 5945-33-5 Sub-chronic toxicity (90-day): oral 01/09/2010 15/10/2010 Details
(3-chloropropyl)dimethoxymethylsilane 242-056-0 18171-19-2 Sub-chronic toxicity (90-day): oral 25/05/2020 09/07/2020 Details
(E)-7,11-dimethyl-3-methylenedodeca-1,6,10-triene 242-582-0 18794-84-8 Sub-chronic toxicity (90-day): oral 23/04/2018 07/06/2018 Details
1,2,4,5,7,8-Hexoxonane, 3,6,9-trimethyl-, 3,6,9-tris(Ethyl and Propyl) derivatives - - Sub-chronic toxicity (90-day): oral 30/06/2016 15/08/2016 Details
1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl triesters 290-754-9 90218-76-1 Sub-chronic toxicity (90-day): oral 29/07/2011 12/09/2011 Details
1,2-diacetoxybut-3-ene 421-720-5 18085-02-4 Sub-chronic toxicity (90-day): oral 25/11/2021 10/01/2022 Details
1,3-diethyldiphenylurea 201-645-2 85-98-3 Sub-chronic toxicity (90-day): oral 03/03/2014 17/04/2014 Details
1,3-Propanediamine, N-[3-((C11-14, C13-rich)oxy)propyl]- branched acetate 931-295-2 - Sub-chronic toxicity (90-day): oral 25/05/2020 09/07/2020 Details
1-[bis[3-(dimethylamino)propyl]amino]propan-2-ol 266-587-2 67151-63-7 Sub-chronic toxicity (90-day): oral 21/03/2014 05/05/2014 Details
1-ethynylcyclohexanol 201-100-9 78-27-3 Sub-chronic toxicity (90-day): oral 18/02/2014 04/04/2014 Details
2,2'-[oxybis(methylene)]-bis[2-ethylpropane-1,3-diol] 245-509-0 23235-61-2 Sub-chronic toxicity (90-day): oral 30/09/2015 16/11/2015 Details
2,2'-ethylenedioxydiethyl bis(2-ethylhexanoate) 202-319-2 94-28-0 Sub-chronic toxicity (90-day): oral 26/01/2011 14/03/2011 Details
2,2'-oxybis[5,5-dimethyl-1,3,2-dioxaphosphorinane] 2,2'-disulphide 223-829-1 4090-51-1 Sub-chronic toxicity (90-day): oral 16/06/2022 01/08/2022 Details
2,2,6,6-tetramethyl-4-oxopiperidinooxy 220-778-7 2896-70-0 Sub-chronic toxicity (90-day): oral 03/04/2023 22/05/2023 Details
2,4-di-tert-butylphenol 202-532-0 96-76-4 Sub-chronic toxicity (90-day): oral 16/05/2011 30/06/2011 Details
2,5-di-tert-pentylhydroquinone 201-222-2 79-74-3 Sub-chronic toxicity (90-day): oral 31/05/2011 15/07/2011 Details
2,6-di-tert-butylphenol 204-884-0 128-39-2 Sub-chronic toxicity (90-day): oral 16/05/2011 30/06/2011 Details
2-[2,2-bis(2-prop-2-enoyloxyethoxymethyl)butoxy]ethyl 3-(dibutylamino)propanoate 701-363-4 - Sub-chronic toxicity (90-day): oral 26/08/2021 11/10/2021 Details
2-aminoethanol, monoester with boric acid 233-829-3 10377-81-8 Sub-chronic toxicity (90-day): oral 17/11/2011 02/01/2012 Details
2-Butenoic acid, 4-oxo-4-(tridecylamino)-, (Z)-, branched 283-219-6 84583-68-6 Sub-chronic toxicity (90-day): oral 12/04/2017 29/05/2017 Details
2-ethylaminoethanol 203-797-5 110-73-6 Sub-chronic toxicity (90-day): oral 18/02/2014 04/04/2014 Details
2-methylbut-3-yn-2-ol 204-070-5 115-19-5 Sub-chronic toxicity (90-day): oral 20/04/2015 08/06/2015 Details
2-piperazin-1-ylethylamine 205-411-0 140-31-8 Sub-chronic toxicity (90-day): oral 21/10/2011 05/12/2011 Details
2-Propenoic acid, 1,1'-[(1-methyl-1,2-ethanediyl)bis[oxy(methyl-2,1-ethanediyl)]] ester, reaction products with diethylamine 601-101-8 111497-86-0 Sub-chronic toxicity (90-day): oral 18/02/2021 05/04/2021 Details
2-Propyn-1-ol, compd. with methyloxirane 609-530-2 38172-91-7 Sub-chronic toxicity (90-day): oral 16/10/2014 01/12/2014 Details
3,5,5-trimethylhexyl 3,5,5-trimethylhexanoate 261-665-2 59219-71-5 Sub-chronic toxicity (90-day): oral 24/02/2020 09/04/2020 Details
3-(Diisobutoxy-thiophosphorylsulfanyl)-2-methyl-propionic acid 434-070-2 - Sub-chronic toxicity (90-day): oral 18/02/2013 04/04/2013 Details
3-C12-14-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide 931-324-9 - Sub-chronic toxicity (90-day): oral 02/09/2011 17/10/2011 Details
3-methoxy-3-methylbutan-1-ol 260-252-4 56539-66-3 Sub-chronic toxicity (90-day): oral 18/09/2014 03/11/2014 Details
4,4'-[(isopropylidene)bis(p-phenyleneoxy)]diphthalic dianhydride 253-781-7 38103-06-9 Sub-chronic toxicity (90-day): oral 27/01/2020 12/03/2020 Details
4-(1-methyl-1-phenylethyl)-N-[4-(1-methyl-1-phenylethyl)phenyl]aniline 233-215-5 10081-67-1 Sub-chronic toxicity (90-day): oral 18/02/2014 04/04/2014 Details
4-methylmorpholine 203-640-0 109-02-4 Sub-chronic toxicity (90-day): oral 25/11/2021 10/01/2022 Details
4-morpholinecarbaldehyde 224-518-3 4394-85-8 Sub-chronic toxicity (90-day): oral 04/04/2014 19/05/2014 Details
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one 403-830-5 89331-94-2 Sub-chronic toxicity (90-day): oral 02/09/2013 18/10/2013 Details
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one 403-830-5 89331-94-2 Sub-chronic toxicity (90-day): oral 26/03/2018 11/05/2018 Details
7-amino-3,8-bis-[4-(2-sulfoxyethylsulfonyl)-2-sulfophenylazo]-4-hydroxynaphthalene-2-sulfonic acid, Na/K salt; 7-amino-3-[4-(2-sulfoxyethylsulfonyl)phenylazo]-4-hydroxy-8-[4-(2-sulfoxyethylsulfonyl)-2-sulfophenylazo]naphthalene-2-sulfonic acid, Na/K salt; 7-amino-8-[4-(2-sulfoxyethylsulfonyl)-phenylazo]-4-hydroxy-3-[4-(2-sulfoxyethylsulfonyl)-2-sulfophenylazo]naphthalene-2-sulfonic acid, Na/K salt; reaction mass of: 7-amino-3,8-bis-[4-(2-sulfoxyethylsulfonyl)phenylazo]-4-hydroxynaphthalene-2-sulfonic acid, Na/K salt 429-070-4 - Sub-chronic toxicity (90-day): oral 22/04/2021 07/06/2021 Details
Acetalization products between glucose and C16-18(even numbered)- alcohol 927-870-2 - Sub-chronic toxicity (90-day): oral 15/09/2011 31/10/2011 Details
Acetalization products between glucose and C20-22(even numbered)- alcohol 923-835-0 - Sub-chronic toxicity (90-day): oral 15/09/2011 31/10/2011 Details
ALCOHOLS, C11-14-ISO-, C13-RICH 271-235-6 68526-86-3 Sub-chronic toxicity (90-day): oral 31/05/2016 15/07/2016 Details
ALCOHOLS, C7-9-ISO-, C8-RICH 271-231-4 68526-83-0 Sub-chronic toxicity (90-day): oral 31/05/2016 15/07/2016 Details
Alkenes, C13-14 931-071-4 - Sub-chronic toxicity (90-day): oral 25/06/2012 09/08/2012 Details
Alkenes, C6-8, even and odd, linear and branched - - Sub-chronic toxicity (90-day): oral 25/06/2012 09/08/2012 Details
Amides, C16-C18 (even) , N,N'-ethylenebis 931-299-4 - Sub-chronic toxicity (90-day): oral 16/08/2011 30/09/2011 Details
Amines, C11-14-branched alkyl, monohexyl and dihexyl phosphates 279-632-6 80939-62-4 Sub-chronic toxicity (90-day): oral 23/11/2020 07/01/2021 Details
Benzenamine, reaction products with aniline hydrochloride and nitrobenzene, hydrochlorides 309-913-1 101357-16-8 Sub-chronic toxicity (90-day): oral 21/09/2020 05/11/2020 Details
Benzoic acid, 2-hydroxy-, mono-C>13-alkyl derivs., calcium salts (2:1) 281-018-8 83846-43-9 Sub-chronic toxicity (90-day): oral 18/06/2018 02/08/2018 Details
Bis(2,4,4-trimethylpentyl)phosphinic acid 280-445-7 83411-71-6 Sub-chronic toxicity (90-day): oral 18/03/2021 03/05/2021 Details
Bis(triethoxysilylpropyl)amine 236-818-1 13497-18-2 Sub-chronic toxicity (90-day): oral 22/09/2022 07/11/2022 Details
bismuth hydroxide nitrate oxide 215-136-8 1304-85-4 Sub-chronic toxicity (90-day): oral 18/09/2014 03/11/2014 Details
Butyl (dialkyloxy(dibutoxyphosphoryloxy))titanium(trialkyloxy)titanium phosphate 401-100-0 - Sub-chronic toxicity (90-day): oral 27/05/2019 11/07/2019 Details
Butyl glycollate 230-991-7 7397-62-8 Sub-chronic toxicity (90-day): oral 15/04/2011 30/05/2011 Details
calcium bis(di C8-C10, branched, C9 rich, alkylnaphthalenesulphonate) 939-717-7 - Sub-chronic toxicity (90-day): oral 02/06/2014 17/07/2014 Details
Camphene 201-234-8 79-92-5 Sub-chronic toxicity (90-day): oral 24/02/2020 09/04/2020 Details
Cyclohexylidenebis[tert-butyl] peroxide 221-111-2 3006-86-8 Sub-chronic toxicity (90-day): oral 21/03/2014 05/05/2014 Details
Dimethoxymethylsilane 240-914-9 16881-77-9 Sub-chronic toxicity (90-day): oral 25/05/2020 09/07/2020 Details
Disilver oxide 243-957-1 20667-12-3 Sub-chronic toxicity (90-day): oral 15/04/2011 30/05/2011 Details
Dodecene, hydroformylation products, low-boiling 271-240-3 68526-92-1 Sub-chronic toxicity (90-day): oral 29/04/2014 13/06/2014 Details
Dodecyl methacrylate 205-570-6 142-90-5 Sub-chronic toxicity (90-day): oral 03/04/2023 22/05/2023 Details
Ethylene dimethacrylate 202-617-2 97-90-5 Sub-chronic toxicity (90-day): oral 03/10/2023 17/11/2023 Details
Glycerol, propoxylated, esters with acrylic acid 500-114-5 52408-84-1 Sub-chronic toxicity (90-day): oral 22/11/2017 08/01/2018 Details
Guanidinium phosphate (1:1) 226-551-9 5423-22-3 Sub-chronic toxicity (90-day): oral 16/05/2014 30/06/2014 Details
hexahydrophthalic acid diglycidylester 696-026-0 1395383-69-3 Sub-chronic toxicity (90-day): oral 16/10/2014 01/12/2014 Details
Hydroxyethylated 2-butyne-1,4-diol 608-711-3 32167-31-0 Sub-chronic toxicity (90-day): oral 17/06/2014 01/08/2014 Details
Imidazolium compounds, 2-C17-unsatd.-alkyl-1-(2-C18-unsatd. amidoethyl)-4,5-dihydro-N-methyl, Me sulfates 931-745-8 - Sub-chronic toxicity (90-day): oral 01/07/2011 15/08/2011 Details
Isononanoic acid, C16-18 (even numbered)-alkyl esters 601-141-6 111937-03-2 Sub-chronic toxicity (90-day): oral 18/09/2014 03/11/2014 Details
Isononyl isononanoate 609-993-0 42131-25-9 Sub-chronic toxicity (90-day): oral 18/09/2014 03/11/2014 Details
l-Glutamic acid, N-coco acyl derivs., disodium salts 269-085-1 68187-30-4 Sub-chronic toxicity (90-day): oral 22/09/2022 07/11/2022 Details
methyl-1h-benzotriazole 249-596-6 29385-43-1 Sub-chronic toxicity (90-day): oral 16/12/2020 01/02/2021 Details
N,N-bis(2-ethylhexyl)-5-methyl-1H-benzotriazole-1-methylamine, N,N-bis(2-ethylhexyl)-4-methyl-1H-benzotriazole-1-methylamine, 2H-Benzotriazole-2-methanamine, N,N-bis(2-ethylhexyl)-4-methyl-, 2H-Benzotriazole-2-methanamine, N,N-bis(2-ethylhexyl)-5-methyl-, 1H-Benzotriazole-1-methanamine, N,N-bis(2-ethylhexyl)-6-methyl-(Mixture) 939-700-4 - Sub-chronic toxicity (90-day): oral 21/10/2019 05/12/2019 Details
N-[(3-methyl-1H-pyrazol-1-yl)methyl]acetamide; N-[(5-methyl-1H-pyrazol-1-yl)methyl]acetamide 700-208-8 - Sub-chronic toxicity (90-day): oral 04/10/2018 19/11/2018 Details
O,O,O-triphenyl phosphorothioate 209-909-9 597-82-0 Sub-chronic toxicity (90-day): oral 16/12/2016 30/01/2017 Details
Octadecylamine, reaction products with 4,4'-methylenediphenyl diisocyanate 928-226-3 - Sub-chronic toxicity (90-day): oral 16/10/2014 01/12/2014 Details
Octylphosphonic acid 225-218-5 4724-48-5 Sub-chronic toxicity (90-day): oral 03/04/2023 22/05/2023 Details
Pentane-1,2-diol 226-285-3 5343-92-0 Sub-chronic toxicity (90-day): oral 16/06/2011 01/08/2011 Details
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