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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Modern GLP study peformed on the basis of EC directive 92/69/EEC A.1.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1994

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Principles of method if other than guideline:
Not applicable.
GLP compliance:
yes
Type of method:
capillary method

Test material

Constituent 1
Reference substance name:
PTH-decahydroamide
IUPAC Name:
PTH-decahydroamide
Constituent 2
Reference substance name:
Ro 31-9373/000
IUPAC Name:
Ro 31-9373/000
Details on test material:
The test material received from F. Hoffmann-La Roche Ltd was a white solid powder from lot no. 25927 with a purity of 99.8%.

Results and discussion

Melting / freezing point
Melting / freezing pt.:
115.5 - 116.6 °C

Any other information on results incl. tables

The following melting temperature ranges for PTH-Decahydroamide were measured;

115.6 -116.6 ⁰C

115.4 -116.5 ⁰C

115.6 -116.7 ⁰C

The average melting point of PTH-decahydroamide (Ro 31 -9373/000) was determined to be 115.5 -116.6 ⁰C.

No decomposition of the test substance was noticed before the melting temperature is reached.

Applicant's summary and conclusion

Conclusions:
The melting point of PTH-decahydroamide (Ro 31 -9373/000) was determined to be 115.5 -116.6 ⁰C.
Executive summary:

The melting point of PTH-decahydroamide was obtained using the EU method A.1. The melting point of PTH-decahydroamide (Ro 31 -9373/000) was determined to be 115.5 -116.6 ⁰C.