Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 939-401-9 | CAS number: 1469983-41-2
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
There are no specific studies available on the kinetics, metabolism and distribution of AKD in mammals, including humans. However, AKD is expected to be rapidly absorbed from the intestine due to its high lipophilicity (log Kow > 6). In an OECD 422 screening and a 90 day feeding study AKD caused effects in various organs, indicating a wide distribution in the body.
A recent Toxicokinetics study completed on structurally related AKD notified as a new chemical in the EU under Directive 92/32/EEC demonstrated that dermal absorption is very low. The full report can be supplied in confidence if required.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
