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Stability in organic solvents and identity of relevant degradation products

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Reference
Endpoint:
stability in organic solvents and identity of relevant degradation products
Data waiving:
study technically not feasible
Justification for data waiving:
the study does not need to be conducted because the stability of the substance is not considered to be critical
Conclusions:
Solubility (Solvents)
- acetonitrile: approx. 150 g/l (Temperature: 27 °C)
- chloroform: approx. 60 g/l (Temperature: 27 °C)
- dichloromethane: approx. 15 g/l (Temperature: 27 °C)
- Ethyl acetate: approx. 80 g/l (Temperature: 27 °C)
- ethyl alcohol abs.: > 300 g/l
- Methanol: > 500 g/l (Temperature: 26 °C)
- Toluene: approx. 2 g/l (Temperature: 28 °C)

Ref: Physicochemical Data of CGP 48933

Description of key information

The study does not need to be conducted because the stability of the substance is not considered to be critical.

Additional information

Solubility (Solvents)

- acetonitrile: approx. 150 g/l (Temperature: 27 °C)

- chloroform: approx. 60 g/l (Temperature: 27 °C)

- dichloromethane: approx. 15 g/l (Temperature: 27 °C)

- Ethyl acetate: approx. 80 g/l (Temperature: 27 °C)

- ethyl alcohol abs.: > 300 g/l

- Methanol: > 500 g/l (Temperature: 26 °C)

- Toluene: approx. 2 g/l (Temperature: 28 °C)

Ref: Physicochemical Data of CGP 48933