Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 204-820-1 | CAS number: 127-06-0
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The 14-day NOEC, based on growth, was calculated to be 50 mg/L, for the fish, Oryzias latipes.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 50 mg/L
Additional information
No reliable long-term toxicity data are available for the toxicity of acetone oxime to fish. However supporting measured data are available for the analogue, butanone oxime, and included in the dossier.
Kurume Laboratory (1998) provided a reliable (Klimisch 1) GLP compliant study following OECD 304 methods. Juvenile Medaka,Oryzias latipes, were exposed to the analogue, butanone oxime, in a flow-through system for14 days. The 14-day LC50, based on mortality and NOEC, based on growth, are calculated to be >100 mg/L and 50 mg/L, respectively. Consequently, the NOEC value will be taken for the long-term toxicity to fish endpoint.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
