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EC number: 429-330-7
CAS number: 110057-45-9
Primary skin irritation/corrosion study with
PDTN in the rabbit (4 -hour semi-occlusive application).
The study was carried out based on the
guidelines described in: EC Commission Directive 92/69/EEC, 8.4 and OECD
No.404. Three rabbits were exposed to 0.5 grams of PDTN, applied onto the
clipped skin for 4 hours using a semi-occlusive dressing. Observations
were made 1, 24, 48 and 72 hours after exposure. No skin irritation was
caused by 4 hours exposure to PDTN. Based on the results and according
to the OECD-GHS criteria for classification, PDTN does not have to be
classified for skin irritation.
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