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The biodegradation of (R)-3-Amino-2-(2,4-difluorophenyl)-1,1-difluoro-1-(5-(4-(2,2,2-trifluoroethoxy)phenyl)pyridin-2-yl)propan-2-ol L-tartrate was studied in aerobic activated sludge from a domestic wastewater plant according to OECD guideline 301F and EEC method 440/2008/EC C.4 -D in a manometric respirometry test.

(R)-3-Amino-2-(2,4-difluorophenyl)-1,1-difluoro-1-(5-(4-(2,2,2-trifluoroethoxy)phenyl)pyridin-2-yl)propan-2-ol L-tartrate never reached 10 % degradation during the incubation period of 28 days. The mean biodegradation at test end after 28 days was 0% (ThODNH4, ThODNO3).

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