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EC number: 701-173-1
CAS number: -
No sediment toxicity data is available for the test substance.
Annex X states that this study need not be conducted if the chemical
safety assessment does not indicate a need to further investigate the
effects on sediment organisms (column 2).
test substance is covered by the category approach of methylenediphenyl
diisocyanates (MDI). Hence, data of the category substances can be used
to cover this endpoint. The read-across category justification document
is attached in IUCLID section 13. It is important to note that the MDI
category approach for read-across of environmental and human hazards
between the MDI substances belonging to the MDI category is work in
progress under REACH. Therefore the read-across document should be
considered a draft.
The test substances of the methylenediphenyl isocyanate (MDI) category
react quickly with water and hence will be rapidly hydrolysed in contact
with aqueous media (T1/2 = 20h). However, MDI is hydrophobic and poorly
soluble in water and thus the heterogeneous reaction with water or soil
is less rapid. The major product of such a reaction is a solid,
insoluble polyurea. Under conditions typical of many types of
environmental contact, i. e. with relatively poor dispersion of the
denser isocyanate, the interfacial reaction leads to the formation of a
solid crust encasing partially or unreacted material. This crust
restricts ingress of water and egress of amine, and hence slows and
All methylenediphenyl isocyanates are produced in closed systems.
Formation of insoluble polyurea due to the presence of water would cause
abrasion problems and blockage of valves and pipes. Therefore,
production plant releases of MDI to effluents are expected to be
non-existent. Releases to soil and sediment are also expected to be
Furthermore, the EUSES program has been used to calculate PEC values
based on measured emission data provided by MDI producers and
processors, including polyurethane producers (EU MDI Risk Assessment
Report: methylenediphenyl diisocyanate (MDI), 2005). Calculated PEC
values were 6.87 x 10-3 mg/L for freshwater, 5.43 x 10-4 for saltwater,
negligible for sediment and 0.239 mg/kg for soils/grassland. The
corresponding PEC/PNEC ratios would be less than 1.
Taking into account the scientific and exposure arguments, it appears
appropriate to waive the acute and long-term toxity test to sediment
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