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EC number: 234-909-0
CAS number: 12039-88-2
Pre-experiment for toxicity and Main experiments I and II: Result tables
are attched in box "Attached background material"
In a reverse gene mutation assay in bacteria (OECD 471) strains of S.
typhimurium (TA98, TA100, TA1535, TA1537, TA102) were exposed to
Tungsten disilicide (> 88% purity) in DMSO at concentrations of 31.6,
100, 316, 1000, 2000 and 5000 μg/plate (experiment 1: plate
incorporation, experiment 2: pre-incubation) in the presence and absence
of mammalian metabolic activation.
Tungsten disilicide was tested up to the limit dose (5.0 mg/plate). Tungsten
disilicide did not cause gene mutations by base pair changes or
frameshifts in the genome of the tester strains used.
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