Registration Dossier
Registration Dossier
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EC number: 232-650-8 | CAS number: 9002-07-7
Endpoint summary
Administrative data
Description of key information
- Under the conditions of the test, endopeptidase batch PPF38268 was found not to be toxic to Daphnia magna at a nominal concentration up to 100 mg TOS/L (24.7 mg aep/L) after 48h exposure. Thus, no 48h EC50 could be calculated and must be > 100 mg TOS/L (> 24.7 mg aep/L).
- The toxicity of trypsin in algae was not tested, however, an enzyme from the same sub-subclass - sedolisin - was tested.
There was no dose-response relationship and because of the low observed toxicity towards algal growth no ErC50 value could be estimated and must be > 100 mg TOS/L (> 24.7 mg aep/L). The NOEC value was determined to be < 10 mg TOS/L (< 2.5 mg aep/L). Due to the similarity between the two enzymes, similar results are expected for trypsin.
Additional information
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