β-Alanine, N-coco alkyl derivs.

Short-term toxicity to fish

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

short-term toxicity to fish

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 203 (Fish, Acute Toxicity Test)

Deviations:

no

GLP compliance:

yes

Analytical monitoring:

no

Test organisms (species):

Oncorhynchus mykiss (previous name: Salmo gairdneri)

Test type:

semi-static

Water media type:

freshwater

Limit test:

no

Total exposure duration:

96 h

Test temperature:

13 ± 1°C

pH:

8.0

Nominal and measured concentrations:

Nominal concentrations of 0.46, 1.0, 2.2, 4.6 and 10 mglL

Duration:

96 h

Dose descriptor:

LC50

Effect conc.:

3.2 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mortality (fish)

Conclusions:

Exposure to the test item gave LC50 (96 h) 3.2 mg/L.

Executive summary:

A study was performed to assess the acute toxicity of Lakeland ACP 70 to rainbow trout (Oncorhynchus mykiss) under semi-static conditions. The study was conducted in accordance with the EEC Methods for Determination of Ecotoxicity Annex to Directive 92/69/EEC (OJ. No. L383A, 29.12.92) Part C, Method 1 "Acute toxicity for Fish" and the OECD Guideline for Testing of Chemicals No. 203 "Fish, Acute Toxicity Test". Groups of seven juvenile fish were exposed to a range of concentrations of Lakeland ACP 70 dispersed in water. Observations were made on the numbers of dead fish and the incidence of sublethal effects after 3, 6, 24, 48, 72 and 96 hours exposure. Results were reported as LC50 (96 h) 3.2 mg/L.

Reference 2

Endpoint:

short-term toxicity to fish

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 203 (Fish, Acute Toxicity Test)

Deviations:

no

GLP compliance:

yes

Analytical monitoring:

no

Test organisms (species):

other: Scophthalmus maximus

Test type:

semi-static

Water media type:

saltwater

Remarks:

artifical seawater

Limit test:

no

Total exposure duration:

96 h

Test temperature:

15.5 ± 1.5°C.

pH:

- Mean pH 7.70 to 7.86 during definitive study

Nominal and measured concentrations:

Nominal concentrations of 1.0, 1.78, 3.16, 5.62 and 10.0 mg/L test item

Duration:

96 h

Dose descriptor:

LC50

Effect conc.:

3.6 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mortality (fish)

Conclusions:

Exposure of juvenile turbot to the test item gave LC50 (96 h) 3.6 mg/L.

Executive summary:

A sample of ACP 70 was assessed for its potential toxicity to juvenile turbot in a semi-static test over 96 hours in accordance with the PARCOM method 1995, OECD guideline 203. Nominal test concentrations of ACP 70 were prepared over the range of 1.0 mg 1-1 to 10.0 mg 1-1. Juvenile turbot were exposed to the test concentrations in order to determine the concentration which killed 50% of the test organisms over 96 hours (LC50). Results were reported as LC50 (96 h) 3.6 mg/L.

Description of key information

Results are available for one species of freshwater fish and one species of marine fish.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish

Effect concentration:

3.2 mg/L

Marine water fish

Marine water fish

Effect concentration:

3.6 mg/L