Registration Dossier
Registration Dossier
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EC number: 284-219-9 | CAS number: 84812-94-2
Endpoint summary
Administrative data
Description of key information
Abiotic degradation; Hydrolysis: The study does not need to be conducted because the substance is readily biodegradable.
Biodegradation: The substance is considered to be readily biodegradable.
Bioaccumulation: EpiSuite (BCFBAF v3.01) estimates BCF to be 3.162 L/kg wet weight,
Adsorption coefficient: EpiSuite (KOCWIN v2.00) estimates that Log Koc lies in the range 1.43 to 2.81 (dimensionless).
Additional information
Biodegradation
In the key study, test material containing 70% carbon by weight was evaluated using OECD 301 B and test material gave > 60% degradation relative to the ThCO2 value with a maximum of 75.1% recorded on Day 17. For complex mixtures a stepwise, sequential adaptation of the microorganisms to the individual substance components is often observed, the 10-day window does not apply to UVCB substances that are composed of homologous constituents and, in accordance with ECHA Guidance on Information Requirements and Chemical Safety Assessment Chapter R.7b: Endpoint specific guidance (Version 4.0; June 2017), the substance may be considered readily biodegradable because theoretical carbon dioxide (ThCO2) was > 60% over 28 days.
In a supporting study, exposure of enriched natural seawater to the same test material using OECD 306 caused dissolved oxygen concentration to decrease from 7.58 mg O2/L on day zero to 3.53 mg/L on day 28 (dissolved oxygen removal of 47% over 28 days). According to ECHA Guidance on Information Requirements and Chemical Safety Assessment Chapter R.7b: Endpoint specific guidance (Version 4.0; June 2017), the test substance cannot be used to demonstrate ready biodegradability because dissolved oxygen concentration removal was < 70%.
Adsorption coefficient
The substance is expected to have medium affinity for soil because Log Koc is predicted to be > 2 and < 4. No information is currently available to describe pH dependence.
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