Registration Dossier
Registration Dossier
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EC number: 900-043-3 | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- (Q)SAR
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model, but not (completely) falling into its applicability domain, and documentation / justification is limited
- Justification for type of information:
- QSAR prediction
- Guideline:
- other: REACH Guidance on (Q)SAR
- Principles of method if other than guideline:
- (Q)SAR
- Test organisms (species):
- other aquatic crustacea: Daphnid
- Test type:
- other: (Q)SAR
- Water media type:
- freshwater
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 0.059 mg/L
- Validity criteria fulfilled:
- no
- Remarks:
- Aliphatic Amines: Maximum LogKow: 5.0 (Daphnid LC50)
- Conclusions:
- Not conclusive: Validity criteria not fullfilled
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- (Q)SAR
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model, but not (completely) falling into its applicability domain, and documentation / justification is limited
- Justification for type of information:
- QSAR prediction
- Guideline:
- other: REACH Guidance on (Q)SAR
- Principles of method if other than guideline:
- (Q)SAR
- Test organisms (species):
- other aquatic crustacea: Daphnid
- Test type:
- other: (Q)SAR
- Water media type:
- freshwater
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 0.152 mg/L
- Validity criteria fulfilled:
- no
- Remarks:
- Neutral Organic SAR: Maximum LogKow: 5.0 (Daphnid LC50)
- Conclusions:
- Not conclusive: Validity criteria not fullfilled
Referenceopen allclose all
Description of key information
Key value for chemical safety assessment
Additional information
No data could be estimated from ECOSAR as validity criteria is not met.
However, intermediate substance should most likely be deemed to be very toxic to aquatic invertebrates (acute toxicity).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
