Registration Dossier

Physical & Chemical properties

Solubility in organic solvents / fat solubility

Administrative data

Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
14/09/1999 - 15/03/2000
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP, Guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2000
Report date:
2000

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
other: OECD 105
Deviations:
no
Qualifier:
according to guideline
Guideline:
other: EU Annex IIA Point #2.7
Deviations:
no
Qualifier:
according to guideline
Guideline:
other: OPPTS 830.7840
Deviations:
no
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
1-methyl-2-nitro-3-(tetrahydrofuran-3-ylmethyl)guanidine
EC Number:
605-399-0
Cas Number:
165252-70-0
Molecular formula:
C7H14N4O3
IUPAC Name:
1-methyl-2-nitro-3-(tetrahydrofuran-3-ylmethyl)guanidine
Test material form:
other: solid

Results and discussion

Solubility in organic solvents / fat solubilityopen allclose all
Medium:
other: hexane
Solubility:
9 µg/L
Temp.:
20 °C
Medium:
other: heptane
Solubility:
10.5 µg/L
Temp.:
20 °C
Medium:
other: xylene
Solubility:
71.85 mg/L
Temp.:
20 °C
Medium:
toluene
Solubility:
148.6 mg/L
Temp.:
20 °C
Medium:
other: dichloromethane
Solubility:
60.86 g/L
Temp.:
20 °C
Medium:
acetone
Solubility:
57.84 g/L
Temp.:
20 °C
Medium:
methanol
Solubility:
57.18 g/L
Temp.:
20 °C
Medium:
ethanol
Solubility:
19.37 g/L
Temp.:
20 °C
Medium:
ethyl acetate
Solubility:
5.17 g/L
Temp.:
20 °C
Test substance stable:
yes

Applicant's summary and conclusion

Conclusions:
The solubility of dinotefuran in organic solvents is as follows:
At 20 ± 0.5 ºC
Hexane: 9.0 μg/L
Heptane: 10.5 μg/L
Xylene: 71.85 mg/L
Toluene: 148.6 mg/L
Dichloromethane: 60.86 g/L
Acetone: 57.84 g/L
Methanol: 57.18 g/L
Ethanol: 19.37 g/L
Ethyl acetate: 5.17 g/L