Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 235-243-3
CAS number: 12138-09-9
Primary skin irritation/corrosion study with TUNGSTEN DISULFIDE
in the rabbit (4-hour semiocclusive application).
The study was
carried out based on the guidelines described in: EC Commission
Directive 92/69/EEC, 8.4, "Acute Toxicity - Skin irritation" and OECD
No.404, "Acute Dermal Irritation/Corrosion".
Three rabbits were
exposed to 0.5 grams of TUNGSTEN DISULFIDE, applied onto clipped skin
for 4 hours using a semi-occlusive dressing. Observations were made 1,
24, 48 and 72 hours after exposure.
No skin irritation
was caused by 4 hours exposure to TUNGSTEN DISULFIDE.
Grey staining of the treated skin by the test substance was
observed on days 1, 2, 3 and/or 4, which hampered the scoring of the
skin reactions on day 1, but did not hamper the scoring of the skin
reactions on days 2, 3 and 4.
Based on the
results and according to the EC criteria for classification and
labelling requirements for dangerous substances and preparations
(Guidelines in Commission Directive 93/21/EEC), TUNGSTEN DISULFIDE
does not have to be classified and has no obligatory labelling
requirement for skin irritation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again