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EC number: -
CAS number: -
Skin sensitisation: OECD 406; guinea pig maximization. Not sensitising.
Reliability = 1
A Magnusson-Kligman maximization test was conducted with guinea pigs to
determine the potential for the test substance to invoke dermal skin
sensitization reactions. A reading of 0.5 was observed in 3/20 animals
at 30%, 1/20 animals at 10%, and 1/10 animals in the vehicle
control/naïve animal at 30%. A reading of 0.5 (very faint erythema) is
not considered a positive reaction by the scoring system. Based on these
findings and on the evaluation system used, the test substance is not
considered to be a contact skin sensitizer..
There was no evidence of dermal sensitization in guinea pigs. The
substance does not need to be classified for skin sensitization
according to EU Classification, Labelling and Packaging of Substances
and Mixtures (CLP) Regulation (EC) No. 1272/2008.
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