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EC number: -
CAS number: -
Skin: OECD 404; rabbit, no irritation. Reliability = 1Eye: OECD 405; rabbit, slight irritation, cleared by 48 hours. Reliability = 1
application of a single 0.5 mL dermal dose to the shaved intact skin of
rabbits for 4 hours, no dermal irritation was observed at any time point
instillation of 0.1 mL of test substance into the lower conjunctival sac
of the eye of 3 rabbits, slight conjunctival redness (score of 2),
chemosis (score of 2), and discharge (score of 2) were observed in 3
rabbits one hour after test substance instillation. The overall
incidence of irritation decreased with time and all animals were free of
ocular irritation by 48 hours.
The test substance produced slight eye irritation which cleared within
48 hours, but no skin irritation. The substance does not need to be
classified for skin or eye irritation according to EU Classification,
Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC)
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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