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Administrative data

Endpoint:
relative density
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2018-07-12 to 2018-10-22
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 109 (Density of Liquids and Solids)
Qualifier:
according to guideline
Guideline:
EU Method A.3 (Relative Density)
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7300 (Density / Relative Density / Bulk Density)
GLP compliance:
no
Type of method:
air comparison pycnometer (for solids)

Test material

Constituent 1
Chemical structure
Reference substance name:
(2Z)-2-fluoro-3-(morpholin-4-yl)acrylaldehyde
EC Number:
813-789-9
Cas Number:
152873-67-1
Molecular formula:
C7H10FNO2
IUPAC Name:
(2Z)-2-fluoro-3-(morpholin-4-yl)acrylaldehyde
Test material form:
solid
Specific details on test material used for the study:
Name: (2Z)-2-Fluor-3-(morpholin-4-yl)acrylaldehyd (FMA)
Lot Number: BXR82PT
CAS No.: 152873-67-1
Sponsor No. 2950024288
Aggregate State at Room Temperature: Solid
Colour: Brown
Expiry Date: November 01, 2018
Storage Conditions at Test Facility: At 20 °C ± 5 °C, in the dark

Results and discussion

Density
Key result
Type:
relative density
Density:
1.351 g/cm³
Temp.:
20 °C

Applicant's summary and conclusion

Conclusions:
In conclusion, the relative density of (2Z)-2-Fluor-3-(morpholin-4-yl)acrylaldehyd (FMA) was determined to be 1.351.
Executive summary:

Title

(2Z)-2-Fluor-3-(morpholin-4-yl)acrylaldehyd (FMA): Determination of the Relative Density

Purpose

The purpose of the study was to determine the relative density of (2Z)-2-Fluor-3-(morpholin-4-yl)acrylaldehyd (FMA) at a specific temperature by means of a gas comparison pycnometer.

Guidelines/Recommendations

This study was based on the procedures indicated by the following internationally accepted guidelines and recommendations:

-Commission Regulation (EC) No.440/2008 laying down test methods pursuant to Regulation (EC) No.1907/2006 of the European Parliament and of the Council on the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) (originally published as Council Regulation (EC) No.440/2008, corrigendum according to Official Journal of the European Union (EN) dated June 3, 2008, L 143/55), Annex, Part A, A.3.: “Relative Density”, Official Journal of the European Union, L 142, Volume 51, 31 May 2008

-Organisation for Economic Co-operation and Development (OECD), OECD Guidelines for Testing of Chemicals, Guideline No. 109, “Density of Liquids and Solids”, adopted October 02, 2012

-Product Properties Test Guideline OPPTS 830.7300 of the United States Environment Protection Agency (EPA), June 2002

Results:           The relative density of (2Z)-2-Fluor-3-(morpholin-4-yl)acrylaldehyd (FMA) was determined using the gas comparison method at a temperature of 20 °C ± 1 °C.

The determination of the relative density was performed by three-fold measurements of two independent test item samples.

The density of (2Z)-2-Fluor-3-(morpholin-4-yl)acrylaldehyd (FMA) was determined to be 1.351 g/cm³ (= 1351 kg/m³) at 20 °C ± 1 °C.

Conclusion:

In conclusion, the relative density of (2Z)-2-Fluor-3-(morpholin-4-yl)acrylaldehyd (FMA) was determined to be 1.351.

This study is classified acceptable and satisfies the guideline requirements for relative density studies.